Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575779 | 0.92 | CNR1 (0.71) | CNR1CNR2KCNH2 | |
| SCHEMBL3573606 | 0.91 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL3564067 | 0.86 | CNR1 (0.68) | CNR1CNR2KCNH2 | |
| SCHEMBL3578480 | 0.85 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL3178557 | 0.83 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL3577716 | 0.83 | CNR1 (0.60) | CNR1CNR2KCNH2 | |
| SCHEMBL4962970 | 0.82 | CNR1 (0.59) | CNR1CNR2 | |
| SCHEMBL3576200 | 0.82 | CNR1 (0.77) | CNR1CNR2 | |
| SCHEMBL3186010 | 0.80 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL3570823 | 0.80 | CNR1 (0.62) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700634-B2 | (Indol-3-yl) heterocycle derivatives as agonists of the cannabinoid CB1 receptor | N.V. ORGANON (NL) | 2010-04-20 | — | — | US | disclosed |
| EP-1725232-B1 | (INDOL-3-YL)-HETEROCYCLE DERIVATIVES AS AGONISTS OF THE CANNABINOID CB1 RECEPTOR | ORGANON NV (NL) | 2008-01-23 | — | — | EP | disclosed |