SCHEMBL3570823

SCHEMBL3570823

COc1cccc2c(-c3nsc(CN4CCCCC4C)n3)cn(CC3CCCCC3)c12

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.62
CNR2 P34972 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3576200 0.90 CNR1 (0.77) CNR1CNR2
SCHEMBL3578480 0.85 CNR1 (0.61) CNR1CNR2
SCHEMBL3178557 0.83 CNR1 (0.65) CNR1CNR2
SCHEMBL4962970 0.82 CNR1 (0.59) CNR1CNR2
SCHEMBL3573606 0.82 CNR1 (0.62) CNR1CNR2
SCHEMBL3186010 0.80 CNR1 (0.56) CNR1CNR2
SCHEMBL3568666 0.80 CNR1 (0.60) CNR1CNR2
SCHEMBL3575779 0.79 CNR1 (0.71) CNR1CNR2
SCHEMBL3564067 0.79 CNR1 (0.68) CNR1CNR2
SCHEMBL4960272 0.78 CNR1 (0.58) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700634-B2 (Indol-3-yl) heterocycle derivatives as agonists of the cannabinoid CB1 receptor N.V. ORGANON (NL) 2010-04-20 US disclosed
EP-1725232-B1 (INDOL-3-YL)-HETEROCYCLE DERIVATIVES AS AGONISTS OF THE CANNABINOID CB1 RECEPTOR ORGANON NV (NL) 2008-01-23 EP disclosed