Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31772593 | 1.00 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL10533916 | 0.92 | ESR2 (0.51) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL2575205 | 0.86 | ESR2 (0.56) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL8486934 | 0.84 | TRPA1 (0.49) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL1713 | 0.83 | ESR2 (0.67) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL6960970 | 0.83 | ESR2 (0.53) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL31410710 | 0.82 | ESR2 (0.76) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL6957029 | 0.82 | ESR2 (0.51) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL7867991 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG | |
| SCHEMBL360601 | 0.81 | ESR2 (0.59) | ESR2FFAR1AKR1B1PTPN5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1058 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115959962-B | Visible light-promoted halogenated alkane hydrodehalogenation method | 中国科学院兰州化学物理研究所 | 2025-05-23 | — | — | CN | claimed |
| CN-119059978-A | Preparation method of irbesartan and intermediate thereof | 浙江华海药业股份有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-118510512-A | Novel process for the preparation of 4'- (bromomethyl) [1,1' -biphenyl ] -2-carbonitrile | 阿尔第实业有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117986239-A | Irbesartan preparation method | 珠海润都制药股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-112441942-B | Debromination method of sartan intermediate polybrominated substituent | 江苏新瑞药业有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117723686-A | Method for determining potential genotoxic impurities in telmisartan by HPLC | 南京红太阳医药研究院有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117705980-A | Method for determining content of sartan bromodiphenyl oxide in candesartan cilexetil tablet | 河南省药品医疗器械检验院(河南省疫苗批签中心) | 2024-03-15 | — | — | CN | claimed |
| CN-116990417-A | Detection method of bromoalkane genotoxic impurities in irbesartan and intermediate thereof | 浙江金立源药业有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-114478315-B | Method for catalytic reduction of irosartan biphenyl waste residues by using halogen-modified Pd/C catalyst | 山东艾孚特科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116675648-A | Preparation method of telmisartan | 迪嘉药业集团股份有限公司 | 2023-09-01 | — | — | CN | claimed |
| EP-1060165-A1 | METHOD FOR PREPARING N-SUBSTITUTED HETEROCYCLIC DERIVATIVES USING A PHASE-TRANSFER CATALYST | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-12-20 | — | — | EP | claimed |
| US-6162922-A | Method for preparing N-substituted heterocyclic derivatives using a phase-transfer catalyst | BRISTOL-MYERS SQUIBB CO. (US) | 2000-12-19 | — | — | US | claimed |
| WO-1999038847-A1 | METHOD FOR PREPARING N-SUBSTITUTED HETEROCYCLIC DERIVATIVES USING A PHASE-TRANSFER CATALYST | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-05 | — | — | WO | claimed |
| US-5892094-A | Process for preparing 4'-methyl-2-cyanobiphenyl | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-04-06 | — | — | US | claimed |
| EP-0709369-B1 | Method for producing 4'-bromomethyl-2-cyanobiphenyl | SUMIKA FINE CHEMICALS CO LTD (JP) | 1999-01-13 | — | — | EP | claimed |
| EP-0881212-A1 | Production method of aminobenzene compound | Takeda Chemical Industries, Ltd. (JP) | 1998-12-02 | — | — | EP | claimed |
| EP-0853081-A1 | Process for preparing 4'-methyl-2-cyanobiphenyl | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-07-15 | — | — | EP | claimed |
| US-5621134-A | Method for producing 4'-bromomethyl-2-cyanobiphenyl | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1997-04-15 | — | — | US | claimed |
| EP-0709369-A1 | Method for producing 4'-bromomethyl-2-cyanobiphenyl | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1996-05-01 | — | — | EP | claimed |
| US-5321137-A | Process for the preparation of imidazopyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-14 | — | — | US | claimed |