Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4982885 | 0.98 | KDM4E (0.96) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| Potassium SCHEMBL9239558 | 0.98 | KDM4E (0.96) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| 2-Pyrrolidone SCHEMBL9226673 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| SCHEMBL29452971 | 0.77 | ALDH1A1 (0.63) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| Purine SCHEMBL25254163 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| SCHEMBL5748057 | 0.76 | ALDH1A1 (0.61) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| SCHEMBL3896 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| SCHEMBL408916 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| SCHEMBL11486223 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1CDK2RXFP1PAK1 | |
| SCHEMBL5170029 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1CDK2RXFP1PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1045 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112245440-A | Use of tocotrienol derivatives | 北京蔚蓝之源医药科技有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-108484605-A | A kind of chloro- 9- of 2- amino -6-（4- acetoxy-3s-acetyl-o-methyl butyl）The preparation method of purine | 上药康丽（常州）药业有限公司 | 2018-09-04 | — | — | CN | claimed |
| EP-2663309-B1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | INFINITY PHARMACEUTICALS INC (US) | 2017-03-15 | — | — | EP | claimed |
| CN-103648499-B | Processes for preparing isoquinolinones and solid forms of isoquinolinones | 无限药品股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| US-9290497-B2 | Processes for preparing isoquinolinones and solid forms of isoquinolinones | INFINITY PHARMACEUTICALS, INC. (US) | 2016-03-22 | — | — | US | claimed |
| CN-104031048-B | A kind of β-chloroethylnitrosoureas compound and preparation method and use thereof | BEIJING UNIVERSITY OF TECHNOLOGY (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-105294761-A | Impurities of tenofovir disoproxil fumarate or tenofovir, and preparation method thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD | 2016-02-03 | — | — | CN | claimed |
| US-20140371450-A1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | HCR COLLATERAL MANAGEMENT, LLC | 2014-12-18 | — | — | US | claimed |
| CN-104031048-A | Novel beta-chloroethylnitrosourea compounds, and synthesis method and application thereof | UNIV BEIJING TECHNOLOGY | 2014-09-10 | — | — | CN | claimed |
| CN-101856313-B | Association of monosaccharides and adenosine and its cosmetic use | OREAL | 2014-02-19 | — | — | CN | claimed |
| WO-2005023811-A1 | PROCESS FOR THE PREPARATION OF (1S, 4R) -CIS-4-‘2-AMINO-6CHLORO-9H-PURIN-9-YL!-2-CYCLOPENTENE-1-METHANOL | GLAXO GROUP LIMITED (GB) | 2005-03-17 | — | — | WO | claimed |
| WO-2004096286-A2 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096235-A2 | ANTI-CANCER PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| EP-0861841-B1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS COMPANY (JP) | 2001-04-04 | — | — | EP | claimed |
| US-5994541-A | Process for producing 2-amino-6-iodopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-11-30 | — | — | US | claimed |
| CN-1226602-A | Fast culture media for mycobaterium tuberculosis and preparation thereof | LIU ZHAOYUN (CN) | 1999-08-25 | — | — | CN | claimed |
| EP-0861841-A1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1998-09-02 | — | — | EP | claimed |
| US-5264561-A | Reaction with an acid anhydride in the presence of a catalyst such as zirconium oxide, titanium oxide, alumina and acetic anhydride | JAPAN TOBACCO INC. (JP) | 1993-11-23 | — | — | US | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| US-3939089-A | PEROXYSULFATE | TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) | 1976-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371450-A1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | PIK3CA, PDPK1, AKT3 | KDM4E 3595/4885ALDH1A1 3633/4885CDK2 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.