Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232229 | 0.91 | TSHR (0.59) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL27279560 | 0.87 | TSHR (0.54) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL8965903 | 0.86 | TSHR (0.53) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL56496 | 0.86 | TSHR (0.53) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL11051294 | 0.85 | TSHR (0.56) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL8037794 | 0.85 | TSHR (0.52) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL15870307 | 0.85 | TSHR (0.52) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL3410733 | 0.85 | TSHR (0.52) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL2781184 | 0.83 | TSHR (0.59) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL2765415 | 0.83 | TSHR (0.59) | TSHRALDH1A1USP2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 914 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768502-B1 | INK COMPOSITION FOR COSMETIC CONTACT LENSES | JOHNSON & JOHNSON VISION CARE (US) | 2026-04-15 | — | — | EP | claimed |
| US-12071497-B2 | High refractive index, high Abbe compositions | Johnson & Johnson Surgical Vision, Inc. (US) | 2024-08-27 | — | — | US | claimed |
| US-20240150595-A1 | INK COMPOSITION FOR COSMETIC CONTACT LENSES | JOHNSON & JOHNSON VISION CARE (US) | 2024-05-09 | — | — | US | claimed |
| EP-3481897-B9 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2024-04-10 | — | — | EP | claimed |
| US-11891526-B2 | Ink composition for cosmetic contact lenses | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-02-06 | — | — | US | claimed |
| EP-3481897-B1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2024-01-03 | — | — | EP | claimed |
| US-11829008-B2 | Increased stiffness center optic in soft contact lenses for astigmatism correction | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-28 | — | — | US | claimed |
| US-11795252-B2 | Compositions with high refractive index and Abbe number | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-10-24 | — | — | US | claimed |
| EP-3523338-B9 | TRI-BLOCK PREPOLYMERS AND THEIR USE IN SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE (US) | 2023-10-18 | — | — | EP | claimed |
| US-20230279169-A1 | HIGH REFRACTIVE INDEX, HIGH ABBE COMPOSITIONS | Johnson & Johnson Surgical Vision, Inc. | 2023-09-07 | — | — | US | claimed |
| US-20100081772-A1 | PROCESS FOR FORMING SILICONE HYDROGEL ARTICLES HAVING IMPROVED OPTICAL PROPERTIES | JOHNSON & JOHNSON VISION CARE, INC. | 2010-04-01 | — | — | US | claimed |
| EP-2087382-A2 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | Johnson & Johnson Vision Care, Inc. (US) | 2009-08-12 | — | — | EP | claimed |
| EP-2087383-A1 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | Johson & Johnson Vision Care Inc. (US) | 2009-08-12 | — | — | EP | claimed |
| EP-2037971-A2 | ANTIMICROBIAL LENSES, PROCESSES TO PREPARE THEM AND METHODS OF THEIR USE | Johnson & Johnson Vision Care, Inc. (US) | 2009-03-25 | — | — | EP | claimed |
| US-20080273168-A1 | ANTIMICROBIAL LENSES, PROCESSES TO PREPARE THEM AND METHODS OF THEIR USE | JOHNSON & JOHNSON VISION CARE, INC. | 2008-11-06 | — | — | US | claimed |
| WO-2008054667-A1 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-05-08 | — | — | WO | claimed |
| WO-2008054651-A2 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-05-08 | — | — | WO | claimed |
| US-20080103231-A1 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. | 2008-05-01 | — | — | US | claimed |
| WO-2008005147-A2 | ANTIMICROBIAL LENSES, PROCESSES TO PREPARE THEM AND METHODS OF THEIR USE | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-01-10 | — | — | WO | claimed |
| US-20070138692-A1 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. | 2007-06-21 | — | — | US | claimed |