Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232229 | 0.91 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3680977 | 0.89 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1592259 | 0.88 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35712 | 0.86 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27279560 | 0.86 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1133357 | 0.86 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28049824 | 0.86 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL275389 | 0.86 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1132615 | 0.86 | TSHR (0.53) | TSHRTHRBTDP1ALDH1A1USP2 | |
| SCHEMBL8084375 | 0.86 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547762-A | THERMOSETTING RESIN LAYER | BRIDGESTONE CORPORATION (JP) | 1996-08-20 | — | — | US | disclosed |