Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | CDC25B | P30305 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | CDC25A | P30304 | 3/20 | 0.63 |
| ▸ | IDO1 | P14902 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.63 |
| ▸ | TST | Q16762 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17861314 | 0.81 | CDC25B (0.74) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL25970 | 0.77 | MAPT (1.00) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL29351164 | 0.77 | MAPT (1.00) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL1364028 | 0.77 | MAPT (1.00) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL19356853 | 0.77 | MAPT (1.00) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL9163371 | 0.76 | MAPT (0.95) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL6680739 | 0.76 | MAPT (0.95) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL9812440 | 0.76 | MAPT (0.95) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL3411128 | 0.76 | MAPT (0.95) | ALDH1A1MAPTCDC25BMAPK1LMNA | |
| Menadione SCHEMBL9807661 | 0.76 | MAPT (0.95) | ALDH1A1MAPTCDC25BMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118697878-B | Application of CD36 as molecular marker for inhibiting lung cancer meninges metastasis and therapeutic target | 广东省人民医院 | 2025-02-11 | — | — | CN | disclosed |
| CN-118697878-A | Application of CD36 as molecular marker for inhibiting lung cancer meninges metastasis and therapeutic target | 广东省人民医院 | 2024-09-27 | — | — | CN | disclosed |
| EP-3182129-B1 | METHOD OF SCREENING A THERAPEUTIC AGENT FOR K-RAS MUTANT CANCER | RAND BIO SCIENCE INC (KR) | 2018-12-26 | — | — | EP | disclosed |
| EP-3182129-A1 | CHEMICAL INHIBITOR OF P53-SNAIL BINDING AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER DISEASE CONTAINING SAME AS ITS ACTIVE INGREDIENT | RAND Bio Science Inc. (KR) | 2017-06-21 | — | — | EP | disclosed |
| US-9400281-B2 | Method of screening of therapeutic agents for K-Ras mutant driven cancers | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-07-26 | — | — | US | disclosed |
| US-20140147866-A1 | COMPOUND FOR INHIBITING SNAIL-P53 BINDING AND THERAPEUTIC AGENT FOR CANCER INCLUDING THE COMPOUND AS EFFECTIVE COMPONENT | THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (KR) | 2014-05-29 | — | — | US | disclosed |
| US-20120015960-A1 | CHEMICAL INHIBITOR OF P53-SNAIL BINDING AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER DISEASE CONTAINING SAME AS ITS ACTIVE INGREDIENT | THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (KR) | 2012-01-19 | — | — | US | disclosed |
| EP-2377849-A2 | CHEMICAL INHIBITOR OF P53-SNAIL BINDING AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER DISEASE CONTAINING SAME AS ITS ACTIVE INGREDIENT | Pusan National University Industry-University Cooperation Foundation (KR) | 2011-10-19 | — | — | EP | disclosed |
| EP-2203161-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Indiana University Research and Technology Corporation (US) | 2010-07-07 | — | — | EP | disclosed |
| US-7691418-B2 | Composition for inhibiting or preventing the formation of a biofilm | OYSTERSHELL NV (BE) | 2010-04-06 | — | — | US | disclosed |
| WO-2009042544-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2009-04-02 | — | — | WO | disclosed |
| US-20070258913-A1 | Composition for Inhibiting or Preventing the Formation of a Biofilm | OYSTERSHELL NV (BE) | 2007-11-08 | — | — | US | disclosed |
| EP-1796656-A2 | COMPOSITION FOR INHIBITING OR PREVENTING THE FORMATION OF A BIOFILM | Oystershell NV (BE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006029893-A2 | COMPOSITION FOR INHIBITING OR PREVENTING THE FORMATION OF A BIOFILM | OYSTERSHELL NV (BE) | 2006-03-23 | — | — | WO | disclosed |
| WO-2005042442-A3 | 2-METHYLTHIO-1,4-NAPHTHOQUINONE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF | UNIV MAINZ JOHANNES GUTENBERG (DE) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005042442-A2 | 2-METHYLTHIO-1,4-NAPHTHOQUINONE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF | Johannes Gutenberg-Universität Mainz (DE) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258913-A1 | Composition for Inhibiting or Preventing the Formation of a Biofilm | NQO2, NFKBIA, CROCC | ALDH1A1 2205/4885MAPT 4695/4885CDC25B 2143/4885 |
| US-20120015960-A1 | CHEMICAL INHIBITOR OF P53-SNAIL BINDING AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER DISEASE CONTAINING SAME AS ITS ACTIVE INGREDIENT | TP53, TP53BP1, KRAS | ALDH1A1 1990/4885MAPT 1592/4885CDC25B 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.