Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | CDC25B | P30305 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | IDO1 | P14902 | 3/20 | 1.00 |
| ▸ | CDC25A | P30304 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | HSPD1 | P10809 | 2/20 | 1.00 |
| ▸ | HSPE1 | P61604 | 2/20 | 1.00 |
| ▸ | TST | Q16762 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | ATM | Q13315 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Menadione SCHEMBL29351164 | 1.00 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL19356853 | 1.00 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL25970 | 1.00 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL9807661 | 0.98 | MAPT (0.95) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL9812440 | 0.98 | MAPT (0.95) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL9163371 | 0.98 | MAPT (0.95) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL28388399 | 0.98 | MAPT (0.95) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL6680739 | 0.98 | MAPT (0.95) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL3411128 | 0.98 | MAPT (0.95) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Menadione SCHEMBL28234760 | 0.98 | MAPT (0.95) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8568694-B2 | Nanoparticulate probe for in vivo monitoring of tissue oxygenation | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569482-B2 | Nanoparticulate probe for in vivo monitoring of tissue oxygenation | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-10-29 | — | — | US | disclosed |
| US-8066973-B2 | Nanoparticulate probe for in vivo monitoring of tissue oxygenation | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-11-29 | — | — | US | disclosed |
| US-20100172843-A1 | NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-07-08 | — | — | US | disclosed |
| US-7662362-B2 | Paramagnetic spin probes; useful for magnetic resonance imaging techinques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI); lithium phthalocyanine derivatives | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-02-16 | — | — | US | disclosed |
| EP-1991120-A2 | NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION | THE OHIO STATE UNIVERSITY (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007103706-A2 | NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION | THE OHIO STATE UNIVERSITY (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070041909-A1 | Nanoparticulate probe for in vivo monitoring of tissue oxygenation | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-22 | — | — | US | disclosed |
| EP-1677676-A2 | NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-07-12 | — | — | EP | disclosed |
| US-20050203292-A1 | Paramagnetic spin probes; useful for magnetic resonance imaging techinques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI); lithium phthalocyanine derivatives | NIH - DEITR | 2005-09-15 | — | — | US | disclosed |
| WO-2005024442-A2 | NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-03-17 | — | — | WO | disclosed |
| EP-0247513-B1 | PROCESS FOR PRODUCING 2-METHYL-1,4-NAPHTHOQUINONE | Eisai Chemical Co., Ltd. (JP) | 1991-09-11 | — | — | EP | disclosed |
| EP-0247513-A1 | Process for producing 2-methyl-1,4-naphthoquinone | Eisai Chemical Co., Ltd. (JP) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100172843-A1 | NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION | LPO, TNNC1, PPOX | MAPT 1346/4885ALDH1A1 3305/4885MEN1 1340/4885 |
| US-20070041909-A1 | Nanoparticulate probe for in vivo monitoring of tissue oxygenation | LPO, TNNC1, PPOX | MAPT 1225/4885ALDH1A1 3359/4885MEN1 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.