Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 7/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 3/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572358 | 0.87 | SLC6A2 (0.56) | SLC6A2HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL3574473 | 0.85 | SLC6A2 (0.55) | SLC6A2HTR6HTR2A | |
| SCHEMBL3567218 | 0.78 | SLC6A2 (0.76) | SLC6A2HTR6HTR2AMPOTRPM8 | |
| Hydrochloric Acid SCHEMBL3571084 | 0.77 | SLC6A2 (0.74) | SLC6A2HTR6HTR2AMPOTRPM8 | |
| SCHEMBL3577221 | 0.77 | SLC6A2 (0.56) | SLC6A2HTR6HTR2AHTR1AKMT2A | |
| SCHEMBL30091129 | 0.77 | TDO2 (0.52) | HTR6HTR2ATDO2KMT2AFEN1 | |
| Hydrochloric Acid SCHEMBL3574630 | 0.76 | SLC6A2 (0.55) | SLC6A2HTR6HTR2AHTR1A | |
| SCHEMBL3567564 | 0.74 | SLC6A2 (0.44) | SLC6A2HTR6HTR2A | |
| SCHEMBL14469423 | 0.74 | SLC6A2 (0.48) | SLC6A2HTR2AKMT2A | |
| SCHEMBL3579618 | 0.71 | HTR2A (0.59) | SLC6A2HTR6HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645752-B2 | Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors | WYETH LLC (US) | 2010-01-12 | — | — | US | claimed |