⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357572 | 0.80 | — | — | |
| SCHEMBL3104335 | 0.79 | — | — | |
| SCHEMBL5544928 | 0.77 | — | — | |
| SCHEMBL5266610 | 0.74 | — | — | |
| SCHEMBL1016848 | 0.74 | — | — | |
| SCHEMBL2566008 | 0.74 | — | — | |
| SCHEMBL3102938 | 0.74 | — | — | |
| SCHEMBL5537391 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL20678732 | 0.72 | NAMPT (0.38) | — | |
| SCHEMBL18381917 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430992-A | QUINOLINE-3-CARBOXAMIDES AS H-PGDS INHIBITORS | 阿斯特克斯医疗公司 | 2018-08-21 | — | — | CN | claimed |
| CN-104203929-B | The method for preparing the carboxylate of 4 Jia Ji oxazoles 5 | 帝斯曼知识产权资产管理有限公司 | 2017-11-17 | — | — | CN | claimed |
| EP-2091929-A1 | AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS | The European Molecular Biology Laboratory (DE) | 2009-08-26 | — | — | EP | claimed |
| CN-101421257-A | Agents that disrupt cellular replication and their use in inhibiting pathological conditions | EUROPEAN MOLECULAR BIOLOGY LAB EMBL (DE) | 2009-04-29 | — | — | CN | claimed |
| WO-2007107352-A1 | AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS | THE EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2007-09-27 | — | — | WO | claimed |
| CN-116969923-A | Heteroaryl amino compounds, methods of preparation and use thereof | 北京鞍石生物科技有限责任公司 | 2023-10-31 | — | — | CN | disclosed |
| US-10201525-B2 | Tetrazole-substituted arylamides as PX2 and PX2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2019-02-12 | — | — | US | disclosed |
| US-20180280326-A1 | MEDICAMENT FOR PREVENTING OR INHIBITING ACUTE KIDNEY INJURY | NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER (JP) | 2018-10-04 | — | — | US | disclosed |
| US-10071099-B2 | Medicament for suppressing malignant tumor metastasis | NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER (JP) | 2018-09-11 | — | — | US | disclosed |
| CN-108430992-A | QUINOLINE-3-CARBOXAMIDES AS H-PGDS INHIBITORS | 阿斯特克斯医疗公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-107922393-A | Carrying non-aromatic P2,Novel macrocyclic form of factor XIA | 百时美施贵宝公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107660204-A | Method for producing indazole derivative | 葛兰素史克知识产权开发有限公司 | 2018-02-02 | — | — | CN | disclosed |
| US-20070179127-A1 | Sulfonamide compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-5573999-A | FUNGICIDES AND INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | disclosed |
| US-5538940-A | FUNGICIDE, MITICIDE, INSECTICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | disclosed |
| EP-0525516-B1 | Derivatives of beta substituted cinnomic acid | BASF AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0525516-A2 | Derivatives of beta substituted cinnomic acid | BASF Aktiengesellschaft (DE) | 1993-02-03 | — | — | EP | disclosed |