Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.44 |
| ▸ | WNT3A | P56704 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729056 | 0.82 | DYRK1A (0.46) | ALDH1A1MEN1GAAKMT2ACTNNB1 | |
| SCHEMBL2248217 | 0.79 | MEN1 (0.46) | ALDH1A1MEN1GAAKMT2ACTNNB1 | |
| SCHEMBL28413937 | 0.78 | UTRN (0.47) | ALDH1A1MEN1GAAKMT2ANPC1 | |
| SCHEMBL25669894 | 0.78 | POLB (0.46) | ALDH1A1MEN1GAAKMT2ACTNNB1 | |
| SCHEMBL29733131 | 0.77 | PIK3CD (0.47) | ALDH1A1MEN1GAAKMT2ACTNNB1 | |
| Benzo[D]Oxazole SCHEMBL8027820 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL28423207 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21713276 | 0.72 | HDAC6 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL29593464 | 0.72 | HDAC6 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL31702152 | 0.71 | PTPN5 (0.59) | ALDH1A1MEN1GAAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103002863-A | Methods for improving the appearance of hyperpigmented spot(s) with multiple actives | PROCTER & GAMBLE | 2013-03-27 | — | — | CN | disclosed |
| US-7645753-B2 | Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20060205718-A1 | Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2006-09-14 | — | — | US | disclosed |
| CN-1072842-A | The application aspect adjusting wrinkle of skin and/or atrophoderma of N-acetyl-L-cysteine and derivant thereof | ONE PROCTER & GAMBLE PLAZA CIN (US) | 1993-06-09 | — | — | CN | disclosed |
| US-4028353-A | CYANINE DYES, PHOTOGRAPHY | POLAROID CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |
| US-3996215-A | PHOTOGRAPHIC FILTER OR ANTIHALATION DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-12-07 | — | — | US | disclosed |
| US-3976493-A | CYANINE DYES | POLAROID CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3933507-A | LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER | AGFA-GEVAERT, A.G. (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205718-A1 | Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives | SSTR5, SSTR1, SSTR2 | ALDH1A1 934/4885MEN1 1588/4885GAA 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.