Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586185 | 0.92 | LMNA (0.43) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3585679 | 0.92 | LMNA (0.44) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3573413 | 0.92 | LMNA (0.44) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3584461 | 0.92 | LMNA (0.44) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3571600 | 0.91 | LMNA (0.42) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3578904 | 0.91 | LMNA (0.44) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3580626 | 0.91 | LMNA (0.40) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3571486 | 0.91 | LMNA (0.41) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3579622 | 0.90 | CETP (0.43) | LMNAHPGDCNR1MEN1CYP1A2 | |
| SCHEMBL3579168 | 0.90 | SLC2A1 (0.41) | LMNAHPGDCNR1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379036-B | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | claimed |
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |