SCHEMBL3575636

SCHEMBL3575636

CN(C)CCNC(=O)[C@H](CSCc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 9/20 0.63
PPARA Q07869 9/20 0.63
PPARD Q03181 2/20 0.58
CTSS P25774 6/20 0.53
CTSK P43235 4/20 0.53
CTSB P07858 2/20 0.53
CTSL P07711 1/20 0.53
AKT1 P31749 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5403871 0.87 CTSS (0.69) CTSSCTSKCTSBCTSLAKT1
SCHEMBL5522229 0.84 CTSS (0.75) PPARGPPARAPPARDCTSSCTSK
SCHEMBL3589300 0.83 CTSS (0.72) PPARGPPARACTSSCTSKCTSB
SCHEMBL6578337 0.82 PPARG (0.62) PPARGPPARAPPARDCTSSCTSK
SCHEMBL5412129 0.82 PPARG (0.59) PPARGPPARAPPARDCTSSCTSK
SCHEMBL5853138 0.81 PPARA (0.90) PPARGPPARAPPARD
SCHEMBL3582418 0.81 PPARA (0.90) PPARGPPARAPPARD
SCHEMBL3362562 0.81 PPARA (0.90) PPARGPPARAPPARD
SCHEMBL8420238 0.81 PPARG (0.66) PPARGPPARAPPARDCTSSCTSK
SCHEMBL20629400 0.81 PPARG (0.63) PPARGPPARAPPARDCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 PPARG 1668/4885PPARA 2254/4885PPARD 1026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.