Benzyl Fumarate

Benzyl Fumarate

SCHEMBL166653

O=C(O)/C=C\C(=O)OCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 1.00
LMNA P02545 3/20 0.69
AKR1B10 O60218 2/20 0.63
AKR1B1 P15121 2/20 0.63
CA12 O43570 2/20 0.63
CA4 P22748 2/20 0.63
CA6 P23280 2/20 0.63
CA5A P35218 2/20 0.63
CA7 P43166 2/20 0.63
CA9 Q16790 2/20 0.63
CA14 Q9ULX7 2/20 0.63
CA5B Q9Y2D0 2/20 0.63
TTR P02766 1/20 0.56
ALDH1A1 P00352 8/20 0.55
POLB P06746 1/20 0.55
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzyl Fumarate SCHEMBL527836 1.00 HCAR2 (1.00) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL165231 1.00 HCAR2 (1.00) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL9460386 1.00 HCAR2 (1.00) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL9436105 0.98 HCAR2 (0.96) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL9436009 0.98 HCAR2 (0.96) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL10876347 0.98 HCAR2 (0.96) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL9435998 0.98 HCAR2 (0.96) HCAR2LMNAAKR1B10AKR1B1CA12
Benzyl Fumarate SCHEMBL28242442 0.96 HCAR2 (0.93) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL337504 0.94 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL357565 0.94 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12139679-B2 Lubricity modifier for fuels and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-11-12 US claimed
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-05-18 US claimed
EP-4130206-A1 FUEL LUBRICITY IMPROVER AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2023-02-08 EP claimed
CN-113462443-A Diesel antiwear agent composition, preparation method thereof and diesel composition 中国石油化工股份有限公司 2021-10-01 CN claimed
CN-110637040-A Resin composition for epoxy acrylic medium refractive optical lens and preparation method thereof 可奥熙搜路司有限公司 2019-12-31 CN claimed
CN-110637060-A Epoxy acrylate resin composition for medium refractive optical lens and preparation method thereof 可奥熙搜路司有限公司 2019-12-31 CN claimed
WO-2019143560-A9 METHODS FOR PROMOTING MITOCHONDRIAL BIOGENESIS IN NEURAL CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-09-12 WO claimed
WO-2019143560-A1 METHODS FOR PROMOTING MITOCHONDRIAL BIOGENESIS IN NEURAL CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-25 WO claimed
US-20190111016-A1 METHODS OF TREATING MUSCLE AND LIVER DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-04-18 US claimed
WO-2017147505-A1 METHODS OF TREATING MUSCLE AND LIVER DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-08-31 WO claimed
US-20010021739-A1 Latex compositions containing ethylenically unsaturated esters of fatty compounds and applications thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2001-09-13 US claimed
US-6001913-A COATINGS, ADHESIVES AND INKS FROM BLENDS OF PLASTICIZING CROSSLINKABLE ALKENOL ESTER OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACID MONOMER THE UNIVERSITY OF SOUTHERN MISSISSIPPI 1999-12-14 US claimed
US-5885491-A ADDING MONOSACCHARIDE CRYOPROTECTIVE AGENT INTO AN AQUEOUS DISPERSION OF A NANOCAPSULES WHILE MAINTAINING GENTLE STIRRING UNTIL SAME DISSOLVES, FREEZING THE DISPERSION AND DEHYDRATING BY HEATING TO OBTAIN STABLE LYOPHILIZED PRODUCT LABORATORIOS CUSI, S.A. (ES) 1999-03-23 US claimed
EP-0598091-B1 FUNCTIONALIZED POLYMER NANOPARTICLES, METHOD OF PREPARATION AND USE THEREOF PROLABO SA (FR) 1997-09-24 EP claimed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP claimed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP claimed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US claimed
US-4427820-A STYRENE, MALEIC ACID DERIVATIVE, EMULSION POLYMERIZATION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-24 US claimed
US-3990980-A Hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed
US-3991226-A Method of creating an image using hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139679-B2 Lubricity modifier for fuels and application thereof F12, ACADM, ADH1A HCAR2 341/4885LMNA 4078/4885AKR1B10 175/4885
US-20190111016-A1 METHODS OF TREATING MUSCLE AND LIVER DISORDERS CKMT1A; CKMT1B, CPT1B, GLS2 HCAR2 2186/4885LMNA 511/4885AKR1B10 993/4885
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF F12, ACADM, ADH1A HCAR2 341/4885LMNA 4078/4885AKR1B10 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.