SCHEMBL357594

SCHEMBL357594

OCCNCCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.65
GAA P10253 2/20 0.59
MAPT P10636 1/20 0.59
TDP1 Q9NUW8 1/20 0.58
KCNH2 Q12809 2/20 0.57
MPO P05164 1/20 0.53
ATM Q13315 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6895167 0.98 SIGMAR1 (0.63) SIGMAR1GAAMAPTTDP1KCNH2
Diethanolamine SCHEMBL5343789 0.92 GAA (0.74) SIGMAR1GAAMAPTTDP1MPO
SCHEMBL8034862 0.92 SIGMAR1 (0.75) SIGMAR1KCNH2
SCHEMBL283735 0.88 SIGMAR1 (0.81) SIGMAR1GAAMAPTKCNH2ATM
SCHEMBL6897551 0.88 SMN1; SMN2 (0.69) SIGMAR1GAAMAPTKCNH2
SCHEMBL536909 0.87 SIGMAR1 (0.73) SIGMAR1GAAMAPTKCNH2
SCHEMBL3681105 0.87 SIGMAR1 (0.79) SIGMAR1KCNH2
SCHEMBL13937400 0.85 SIGMAR1 (0.77) SIGMAR1GAAMAPTTDP1KCNH2
Hydrochloric Acid SCHEMBL5028920 0.85 SIGMAR1 (0.77) SIGMAR1GAAMAPTKCNH2ATM
SCHEMBL8140699 0.85 SIGMAR1 (0.77) SIGMAR1GAAMAPTTDP1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114749162-B Functionalized chromatographic medium containing polymer nanofibers and preparation method thereof 思拓凡生物工艺研发有限公司 2025-04-08 CN claimed
CN-117659328-A Oxazolidine latent curing agent, preparation method thereof and bi-component polyurethane adhesive 佛山市桐立新材料科技有限公司 2024-03-08 CN claimed
CN-114749162-A Functionalized chromatography media comprising polymeric nanofibers and methods of making the same 纯化迪发有限公司 2022-07-15 CN claimed
CN-109414680-B Functionalized chromatography media comprising polymeric nanofibers and methods of making the same 纯化迪发有限公司 2022-04-19 CN claimed
CN-112898960-A White light luminescent material based on two-dimensional perovskite structure and preparation and application thereof 中国科学院大连化学物理研究所 2021-06-04 CN claimed
EP-3484613-B1 FUNCTIONALISED CHROMATOGRAPHY MEDIUM COMPRISING POLYMER NANOFIBRES AND PROCESS OF PREPARATION THEREOF PURIDIFY LTD (GB) 2021-02-24 EP claimed
EP-3055059-B1 CHROMATOGRAPHY MEDIUM PURIDIFY LTD (GB) 2017-03-08 EP claimed
EP-2661436-B1 NOVEL SULFAMIDE PIPERAZINE DERIVATIVES AS PROTEIN TYROSINE KINASE INHIBITORS AND PHARMACEUTICAL USE THEREOF LEO PHARMA AS (DK) 2016-04-13 EP claimed
US-9233964-B2 Sulfamide piperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use therof LEO PHARMA A/S (DK) 2016-01-12 US claimed
US-20150184215-A1 DEVELOPMENT OF THE SOLUBLE RECOMBINANT CRM197 PRODUCTION BY E. COLI DEV CENTER BIOTECHNOLOGY (TW) 2015-07-02 US claimed
US-5908960-A Compounds SMITHKLINE BEECHAM CORPORATION (US) 1999-06-01 US claimed
US-5403689-A Amide functionality XEROX CORPORATION (US) 1995-04-04 US claimed
EP-0643088-A1 Amino functional polyesters XEROX CORPORATION (US) 1995-03-15 EP claimed
US-5354840-A Functional-amine polyesters XEROX CORPORATION (US) 1994-10-11 US claimed
EP-0202625-B1 PROCESS FOR THE PREPARATION OF 2,6-DIMETHYL-4-(3'-NITROPHENYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID 3-BETA-(N-BENZYL-N-METHYLAMINO)-ETHYL ESTER 5-METHYL ESTER AND ITS HYDROCHLORIDE SALT LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o. (SI) 1990-08-01 EP claimed
EP-0202625-A2 Process for the preparation of 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-(N-benzyl-N-methylamino)-ethyl ester 5-methyl ester and its hydrochloride salt LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o. (SI) 1986-11-26 EP claimed
US-4529384-A Use of cyanoacrylate compounds for dental modeling MDS PRODUCTS, INC. (US) 1985-07-16 US claimed
US-4378213-A USING AN ACCELERATOR TO PROMOTE HARDENING MDS PRODUCTS COMPANY, INC. (US) 1983-03-29 US claimed
WO-1982000756-A1 USE OF CYANOACRYLATE COMPOUNDS FOR DENTAL MODELING SEVERY S 1982-03-18 WO claimed
US-4012542-A PRE-CATALYZED POLYESTER, POLYMERIZATION INHIBITOR, METAL SOAP-AROMATIC TERT-AMINE ACCELERATOR FERRO CORPORATION (US) 1977-03-15 US claimed