Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.69 |
| ▸ | RELA | Q04206 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.67 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | UBE2N | P61088 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576787 | 1.00 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL4135937 | 0.91 | RAB9A (0.76) | SMN1; SMN2RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL4135933 | 0.91 | RAB9A (0.76) | SMN1; SMN2RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL13191415 | 0.84 | RAB9A (0.63) | SMN1; SMN2RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL9587050 | 0.84 | CYP1A1 (0.65) | ALDH1A1AMY1AKDM4ELMNAHPGD | |
| SCHEMBL9587052 | 0.84 | CYP1A1 (0.65) | ALDH1A1AMY1AKDM4ELMNAHPGD | |
| SCHEMBL25772042 | 0.84 | RAB9A (0.66) | SMN1; SMN2RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL7359689 | 0.83 | PDE4A (0.55) | SMN1; SMN2RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL7359690 | 0.83 | PDE4A (0.55) | SMN1; SMN2RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL3568939 | 0.83 | RAB9A (0.68) | SMN1; SMN2RAB9ANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029728-A1 | PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2010-02-04 | — | — | US | disclosed |
| EP-2066661-A2 | PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008035316-A2 | PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029728-A1 | PHOSPHODIESTERASE INHIBITORS | PDE4A, PDE4B, PDE4C | SMN1; SMN2 3397/4885RAB9A 281/4885NPC1 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.