Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.92 |
| ▸ | HTR2A | P28223 | 15/20 | 0.92 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571269 | 0.96 | SLC6A2 (1.00) | SLC6A2HTR2AHTR2CHTR6MEN1 | |
| SCHEMBL3575861 | 0.96 | SLC6A2 (0.96) | SLC6A2HTR2AHTR2CHTR6MEN1 | |
| SCHEMBL3573953 | 0.95 | SLC6A2 (0.98) | SLC6A2HTR2AHTR2CHTR6MEN1 | |
| SCHEMBL3566061 | 0.88 | SLC6A2 (0.73) | SLC6A2HTR2AHTR2CHTR6OPRM1 | |
| SCHEMBL3566194 | 0.84 | HTR2A (1.00) | SLC6A2HTR2AHTR2CHTR6ALDH1A1 | |
| SCHEMBL3571020 | 0.84 | SLC6A2 (0.80) | SLC6A2HTR2AHTR2CHTR6MEN1 | |
| SCHEMBL3568994 | 0.84 | SLC6A2 (0.76) | SLC6A2HTR2AHTR2CHTR6MEN1 | |
| SCHEMBL3570477 | 0.84 | SLC6A2 (0.78) | SLC6A2HTR2AHTR2CHTR6MEN1 | |
| SCHEMBL3571257 | 0.82 | SLC6A2 (0.64) | SLC6A2HTR2AHTR6MEN1ALDH1A1 | |
| SCHEMBL3565595 | 0.81 | SLC6A2 (1.00) | SLC6A2HTR2AHTR2CHTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645752-B2 | Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors | WYETH LLC (US) | 2010-01-12 | — | — | US | claimed |
| CN-101370775-A | Sulfonyl-substituted 1H-indoles as 5-hydroxytryptamine receptor ligands | WYETH CORP (US) | 2009-02-18 | — | — | CN | claimed |
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | claimed |
| US-20070203120-A1 | Sulfonyl Substituted 1H-Indoles as Ligands for the 5-Hydroxytryptamine Receptors | WYETH (US) | 2007-08-30 | — | — | US | claimed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | claimed |
| US-7645752-B2 | Sulfonyl substituted 1H-indoles as ligands for the 5-hydroxytryptamine receptors | WYETH LLC (US) | 2010-01-12 | — | — | US | disclosed |
| CN-101370775-A | Sulfonyl-substituted 1H-indoles as 5-hydroxytryptamine receptor ligands | WYETH CORP (US) | 2009-02-18 | — | — | CN | disclosed |
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | disclosed |
| US-20070203120-A1 | Sulfonyl Substituted 1H-Indoles as Ligands for the 5-Hydroxytryptamine Receptors | WYETH (US) | 2007-08-30 | — | — | US | disclosed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203120-A1 | Sulfonyl Substituted 1H-Indoles as Ligands for the 5-Hydroxytryptamine Receptors | HTR5A, HTR2C, HTR2A | SLC6A2 20/4885HTR2A 3/4885HTR2C 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.