Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid Ethyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL8159679 | 0.89 | TSHR (0.60) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL3180 | 0.89 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL9557413 | 0.89 | TSHR (0.60) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL1284845 | 0.87 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL7076340 | 0.86 | TSHR (0.54) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL584917 | 0.86 | TSHR (0.54) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL23607549 | 0.86 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL15553985 | 0.86 | TSHR (0.58) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL2243109 | 0.86 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL2482159 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118460122-A | Waterproof PVAc white latex and preparation method thereof | 沈阳爱克浩博化工有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118256003-A | CO2Polymer solution/nanosphere compound system responding to tackifying and preparation method thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118239695-A | Hydrophilic film layer and preparation method thereof | 江苏菲沃泰纳米科技股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118240474-A | Composite coating, preparation method and device | 江苏菲沃泰纳米科技股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118239696-A | Method for preparing film layer, film layer and device | 江苏菲沃泰纳米科技股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118060160-A | Method for preparing coating, coating and device | 江苏菲沃泰纳米科技股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117050601-B | Fluorine electronic protective coating and preparation method thereof | 广东聚微新材料科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117801163-A | Bionic amphoteric ion polymer and preparation method and application thereof | 广东省科学院化工研究所 | 2024-04-02 | — | — | CN | claimed |
| CN-117777350-A | Heat-resistant acrylic resin, acrylic pressure-sensitive adhesive for polarizer protective film and preparation method of acrylic pressure-sensitive adhesive | 北京高盟新材料股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-115124659-B | Organosilicon polyurethane material with high blood compatibility and preparation method thereof | 苏州心锐医疗科技有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-112469739-A | High molecular weight polymers from continuous processes | 巴斯夫欧洲公司 | 2021-03-09 | — | — | CN | claimed |
| CN-108409894-B | Method for catalyzing vinyl monomer polymerization reaction by transition metal nanoparticles | 浙江工业大学 | 2020-12-25 | — | — | CN | claimed |
| EP-3710570-A1 | DETERGENTS AND CLEANING PRODUCTS CONTAINING A POLYMER ACTIVE INGREDIENT | Henkel AG & Co. KGaA (DE) | 2020-09-23 | — | — | EP | claimed |
| EP-3710496-A1 | DETERGENTS AND CLEANING PRODUCTS CONTAINING A POLYMER ACTIVE INGREDIENT | Henkel AG & Co. KGaA (DE) | 2020-09-23 | — | — | EP | claimed |
| EP-3710504-A1 | DETERGENT AND CLEANING AGENT WITH POLYMER ACTIVE AGENT | Henkel AG & Co. KGaA (DE) | 2020-09-23 | — | — | EP | claimed |
| CN-107973874-B | High-adhesion conductive self-healing hydrogel and preparation method and application thereof | 北京大学 | 2020-06-02 | — | — | CN | claimed |
| CN-107960081-B | Energy-curable hyperbranched polycarbonate polyol backbone multifunctional acrylate | 巴斯夫欧洲公司 | 2020-04-28 | — | — | CN | claimed |
| CN-106729975-B | Material for producing artificial lens | 爱博诺德(北京)医疗科技股份有限公司 | 2020-04-14 | — | — | CN | claimed |
| CN-107260755-A | The method for treating inflammation | 西托索尔本茨公司 | 2017-10-20 | — | — | CN | claimed |
| CN-103037869-A | Method of treating inflammation | CYTOSORBENTS CORP | 2013-04-10 | — | — | CN | claimed |