SCHEMBL357845

SCHEMBL357845

Oc1c(Cl)ccc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.60
PTPN22 Q9Y2R2 1/20 0.60
CYP1A2 P05177 3/20 0.52
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LDHA P00338 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
ABCG2 Q9UNQ0 1/20 0.46
CYP1A1 P04798 1/20 0.46
CYP1B1 Q16678 1/20 0.46
HPRT1 P00492 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanate SCHEMBL7108623 0.90 CYP2A6 (0.50) CYP2A6PTPN22CYP1A2ALDH1A1TSHR
SCHEMBL11779519 0.89 HPRT1 (0.58) CYP2A6PTPN22CYP1A2ALDH1A1TSHR
SCHEMBL11773669 0.80 CYP2A6 (0.43) CYP2A6PTPN22CYP1A2ALDH1A1HSD17B10
SCHEMBL1470193 0.76 KMT2A (0.58) CYP2A6PTPN22CYP1A2TDP1KDM4E
SCHEMBL23033906 0.76 CYP2A6 (0.52) CYP2A6PTPN22CYP1A2ALDH1A1TSHR
SCHEMBL29401627 0.75 PTPN22 (0.65) CYP2A6PTPN22CYP1A2ALDH1A1TSHR
SCHEMBL29613822 0.75 PTPN22 (1.00) CYP2A6PTPN22CYP1A2ALDH1A1TSHR
SCHEMBL449348 0.75 CYP2A6 (1.00) CYP2A6PTPN22CYP1A2ALDH1A1TSHR
SCHEMBL5673224 0.75 CYP2A6 (0.65) CYP2A6PTPN22CYP1A2ALDH1A1TSHR
SCHEMBL374807 0.75 PTPN22 (0.65) CYP2A6PTPN22CYP1A2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417568-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF THE BOEING COMPANY (US) 2024-12-19 US claimed
EP-4477720-A1 ADHESION PROMOTER FOR COMPOSITES AND METHODS THEREOF The Boeing Company (US) 2024-12-18 EP claimed
CN-119137462-A High sensitivity biological layer interferometry with enzyme amplification 万迈医疗仪器有限公司 2024-12-13 CN claimed
CN-115970727-A Preparation method and application of monatomic nanoenzyme and colorimetric sensor array thereof 东南大学 2023-04-18 CN claimed
CN-115634365-A Universal sterilizing cap 贝克顿·迪金森公司 2023-01-24 CN claimed
CN-112703031-B Universal sterilizing cap 贝克顿·迪金森公司 2022-09-13 CN claimed
CN-114674894-A Construction of GQDs @ ZIF-8 as signal quencher sensor 济南大学 2022-06-28 CN claimed
CN-114674892-A Construction of up-conversion material combined with signal quenching sensing device 济南大学 2022-06-28 CN claimed
CN-114674893-A Construction of sensor based on two-dimensional heterojunction and nanoenzyme combination 济南大学 2022-06-28 CN claimed
CN-113310962-A Rapid colorimetric fluorescent hypochlorite detection reagent 中国科学院新疆理化技术研究所 2021-08-27 CN claimed
US-5238813-A Using solid phase enzyme-linked immunoassay WASHINGTON UNIVERSITY (US) 1993-08-24 US claimed
EP-0474858-A1 A METHOD FOR THE COLLECTION OF ANTIBODIES AND THE DETECTION OF A SPECIFIC ANTIBODY SPECIES IN A FLUID SAMPLE AND A DEVICE FOR CARRYING OUT SAID METHOD AS WELL AS A KIT COMPRISING SAID DEVICE TENTA PROPERTIES N.V. (AN) 1992-03-18 EP claimed
WO-1991014944-A1 A METHOD FOR THE COLLECTION OF ANTIBODIES AND THE DETECTION OF A SPECIFIC ANTIBODY SPECIES IN A FLUID SAMPLE AND A DEVICE FOR CARRYING OUT SAID METHOD AS WELL AS A KIT COMPRISING SAID DEVICE TENTA PROPERTIES N.V. (AN) 1991-10-03 WO claimed
US-4886760-A CHELATE COMPOUND SAVYON DIAGNOSTICS LIMITED (IL) 1989-12-12 US claimed
US-4687736-A Detection of biological substances by specific labelling techniques THE UNIVERSITY OF WALES COLLEGE OF MEDICINE (GB) 1987-08-18 US claimed
EP-0196743-A2 Stable chemical compositions containing chromogenic materials and peroxides, and method for obtaining them SAVYON DIAGNOSTICS LTD. (IL) 1986-10-08 EP claimed
US-4312631-A DISPERSANTS, EMULSIFIERS, WETTING AGENTS, ANIONIC SURFACTANTS HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-26 US claimed
US-4297270-A ETH- OR PROPOXYLATED ESTER DERIVATIVES; DISPERSANTS; EMULSIFIERS; WETTING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1981-10-27 US claimed
US-4146550-A REACTION OF CARBAMIC ACID CHLORIDE WITH ACTIVE HYDROGEN COMPOUND, DECOMPOSITION BAYER AKTIENGESELLSCHAFT (DE) 1979-03-27 US claimed
US-4116879-A Quaternary hydroxyalkyl tertiary amine bases as polyurethane catalysts AIR PRODUCTS AND CHEMICALS, INC. (US) 1978-09-26 US claimed