Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 4/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.31 |
| ▸ | MOGAT2 | Q3SYC2 | 7/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114683 | 1.00 | P2RX3 (0.32) | P2RX3FFAR1FFAR4LRRK2IDH1 | |
| SCHEMBL13135162 | 0.89 | MOGAT2 (0.36) | P2RX3FFAR1FFAR4IDH1MOGAT2 | |
| SCHEMBL14561498 | 0.77 | IDH1 (0.31) | IDH1 | |
| SCHEMBL14561500 | 0.76 | — | — | |
| SCHEMBL2833339 | 0.76 | IDH1 (0.36) | IDH1 | |
| SCHEMBL2833335 | 0.76 | IDH1 (0.36) | IDH1 | |
| SCHEMBL4019944 | 0.76 | IDH1 (0.36) | IDH1 | |
| SCHEMBL2831911 | 0.75 | HSD17B10 (0.36) | IDH1 | |
| SCHEMBL2840076 | 0.75 | CD38 (0.35) | IDH1 | |
| SCHEMBL2840079 | 0.75 | CD38 (0.35) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820647-B2 | 2-substituted pyrimidines and their use as pesticides | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-26 | — | — | US | disclosed |
| US-20080176831-A1 | 2-Substituted Pyrimidines and Their Use as Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-24 | — | — | US | disclosed |
| EP-1751132-B1 | 2-SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | BASF SE (DE) | 2008-03-26 | — | — | EP | disclosed |
| EP-1751132-A1 | 2-SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113538-A1 | 2-SUBSTITUTED PYRIMIDINES AND THEIR USE AS PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176831-A1 | 2-Substituted Pyrimidines and Their Use as Pesticides | CBR1, CBR3, C1R | P2RX3 8/4885FFAR1 875/4885FFAR4 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.