SCHEMBL3579708

SCHEMBL3579708

NC(CNCc1ccccc1)Cc1c[nH]cn1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.44
OPRD1 P41143 2/20 0.40
OPRK1 P41145 2/20 0.40
BCHE P06276 2/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
EPHX1 P07099 1/20 0.36
DNM1 Q05193 1/20 0.35
MMP2 P08253 2/20 0.35
ROCK1 Q13464 1/20 0.35
ATM Q13315 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
BACE1 P56817 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12085515 0.83 MC4R (0.37) ANPEPOPRD1OPRK1HRH4
SCHEMBL3584273 0.80 FNTA (0.41) FNTAFNTBMAOA
SCHEMBL28536404 0.79 MEN1 (0.45) BCHEMEN1KMT2ATDP1ROCK1
SCHEMBL23572993 0.77 EGFR (0.50)
SCHEMBL2445252 0.77 EGFR (0.50)
SCHEMBL421960 0.77 EPHX1 (0.61) ANPEPOPRD1OPRK1BCHEMEN1
SCHEMBL421959 0.77 EPHX1 (0.61) ANPEPOPRD1OPRK1BCHEMEN1
SCHEMBL18539294 0.75 KDM4E (0.42) ANPEPBCHE
SCHEMBL11121889 0.75 EPHX1 (0.59) ANPEPOPRD1OPRK1BCHEMEN1
SCHEMBL4605920 0.75 GAA (0.53) BCHEMEN1KMT2ATDP1HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US claimed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP claimed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO claimed
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 ANPEP 200/4885OPRD1 653/4885OPRK1 878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.