SCHEMBL3584273

SCHEMBL3584273

NC(CNc1ccccc1)Cc1c[nH]cn1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FNTA P49354 3/20 0.41
FNTB P49356 3/20 0.41
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
MAPT P10636 3/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
AKT1 P31749 3/20 0.33
TAAR1 Q96RJ0 2/20 0.33
HRH3 Q9Y5N1 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3579708 0.80 ANPEP (0.44) FNTAFNTBMAOA
SCHEMBL631554 0.76 MAOA (0.55) MAOAMAOBMAPTSMN1; SMN2TAAR1
Histidine SCHEMBL28178306 0.75 SLC7A5 (0.40) MAPT
SCHEMBL3584572 0.75 SCN4A (0.44) MAOAAKT1
Hydrochloric Acid SCHEMBL631888 0.74 MAOA (0.53) MAOAMAOBMAPTSMN1; SMN2TAAR1
SCHEMBL23572978 0.73 LTA4H (0.47)
SCHEMBL21794922 0.73 LTA4H (0.47)
SCHEMBL23572977 0.73 LTA4H (0.47)
SCHEMBL30280698 0.73 GRIN2D (0.57)
SCHEMBL2516273 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US claimed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP claimed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO claimed
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 FNTA 4593/4885FNTB 4421/4885MAOA 3631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.