Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580282 | 0.84 | HTR6 (0.41) | HTR6AKR1B1HTR2CHTR2B | |
| SCHEMBL3535820 | 0.81 | HTR6 (0.43) | HTR6AKR1B1HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3532662 | 0.80 | HTR6 (0.43) | HTR6AKR1B1HTR2CHTR2B | |
| SCHEMBL3531185 | 0.79 | HTR6 (0.43) | HTR6AKR1B1HTR2C | |
| SCHEMBL3532631 | 0.78 | HTR6 (0.39) | HTR6AKR1B1HTR2CHTR2B | |
| SCHEMBL3531881 | 0.78 | HTR1B (0.47) | HTR6AKR1B1 | |
| SCHEMBL3535815 | 0.78 | HTR1D (0.45) | HTR6AKR1B1 | |
| SCHEMBL3532929 | 0.78 | HTR6 (0.49) | HTR6AKR1B1HTR2C | |
| Hydrochloric Acid SCHEMBL3532656 | 0.77 | HTR1D (0.44) | HTR6AKR1B1 | |
| SCHEMBL4837518 | 0.74 | AKR1B1 (0.42) | HTR6AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723329-B2 | Substituted-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH LLC (US) | 2010-05-25 | — | — | US | claimed |