SCHEMBL3580907

SCHEMBL3580907

CC(C)(C)OC(=O)NCCCCC(N)COCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
PPARA Q07869 2/20 0.52
CTSS P25774 1/20 0.52
PPARG P37231 1/20 0.47
KLK7 P49862 2/20 0.47
KLK5 Q9Y337 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.47
SYK P43405 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
IDO1 P14902 1/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
DPP8 Q6V1X1 1/20 0.45
DPP7 Q9UHL4 1/20 0.45
NPSR1 Q6W5P4 2/20 0.45
PAX8 Q06710 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ABCB1 P08183 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3585044 1.00 MAPT (0.53) MAPTPPARACTSSPPARGKLK7
SCHEMBL3594234 0.97 PPARA (0.53) MAPTPPARACTSSPPARGKLK7
SCHEMBL3580162 0.97 PPARA (0.53) MAPTPPARACTSSPPARGKLK7
SCHEMBL3586431 0.92 PPARA (0.55) MAPTPPARACTSSPPARGKLK7
SCHEMBL3580353 0.84 MEN1 (0.53) MAPTPPARACTSSPPARGKLK7
SCHEMBL7979181 0.83 MAPT (0.59) MAPTKLK7KLK5MEN1KMT2A
SCHEMBL5490556 0.83 MAPT (0.59) MAPTKLK7KLK5MEN1KMT2A
SCHEMBL20168169 0.83 MAPT (0.59) MAPTKLK7KLK5MEN1KMT2A
SCHEMBL18490887 0.82 CTSS (0.58) MAPTPPARACTSSPPARGKLK7
SCHEMBL28673469 0.82 MAPT (0.49) MAPTPPARACTSSL3MBTL1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 MAPT 4624/4885PPARA 2254/4885CTSS 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.