⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13440491 | 1.00 | — | — | |
| SCHEMBL3573676 | 0.97 | OPRD1 (0.48) | — | |
| SCHEMBL13441127 | 0.97 | OPRD1 (0.48) | — | |
| SCHEMBL3573669 | 0.97 | OPRD1 (0.48) | — | |
| SCHEMBL13440775 | 0.93 | OPRD1 (0.46) | — | |
| SCHEMBL3575575 | 0.93 | OPRD1 (0.46) | — | |
| SCHEMBL3575739 | 0.93 | — | — | |
| SCHEMBL3571359 | 0.92 | — | — | |
| SCHEMBL13440820 | 0.92 | — | — | |
| SCHEMBL3567230 | 0.91 | OPRD1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683168-B2 | Compositions of novel opioid compounds and method of use thereof | Mount Cook Bio Sciences, Inc. (US) | 2010-03-23 | — | — | US | disclosed |
| EP-1874315-A2 | COMPOSITIONS OF NOVEL OPIOID COMPOUNDS AND METHOD OF USE THEREOF | Mount Cook Biosciences, Inc. (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20070043028-A1 | Compositions of novel opioid compounds and method of use thereof | DMK PHARMACEUTICALS CORPORATION | 2007-02-22 | — | — | US | disclosed |
| WO-2006113468-A2 | COMPOSITIONS OF NOVEL OPIOID COMPOUNDS AND METHOD OF USE THEREOF | MOUNT COOK BIOSCIENCES, INC. (US) | 2006-10-26 | — | — | WO | disclosed |