Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571214 | 0.92 | CNR1 (0.38) | CNR1SCN9ASLC6A9KCNH2STAT3 | |
| SCHEMBL27750943 | 0.92 | CNR1 (0.40) | CNR1SCN9ASLC6A9KCNH2STAT3 | |
| SCHEMBL3586258 | 0.92 | CNR1 (0.34) | CNR1SCN9ASLC6A9KCNH2STAT3 | |
| SCHEMBL3581545 | 0.88 | CNR1 (0.40) | CNR1SLC6A9EPHX2LPAR1LPAR5 | |
| SCHEMBL3578656 | 0.88 | MCL1 (0.37) | CNR1 | |
| SCHEMBL3583320 | 0.87 | CNR1 (0.41) | CNR1SCN9ASLC6A9KCNH2STAT3 | |
| SCHEMBL3586256 | 0.85 | STAT3 (0.35) | CNR1SCN9ASLC6A9KCNH2STAT3 | |
| SCHEMBL27750956 | 0.85 | STAT3 (0.38) | CNR1SCN9ASLC6A9KCNH2STAT3 | |
| SCHEMBL27730487 | 0.84 | CNR1 (0.35) | CNR1SCN9ASLC6A9KCNH2STAT3 | |
| SCHEMBL3583070 | 0.84 | SCN9A (0.40) | CNR1SCN9ASLC6A9KCNH2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |