Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | GIPR | P48546 | 2/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581360 | 0.88 | MCL1 (0.40) | CNR1PPARGPPARDPPARA | |
| SCHEMBL3581035 | 0.88 | CNR1 (0.39) | CNR1EPHX2LPAR1LPAR5SLC6A9 | |
| SCHEMBL3581034 | 0.84 | LPAR1 (0.36) | PPARGPPARDPPARALPAR1LPAR5 | |
| SCHEMBL3570220 | 0.84 | KDM5A (0.40) | PPARGPPARDPPARAEPHX2NR1H4 | |
| SCHEMBL3574035 | 0.83 | MEP1B (0.36) | PPARGPPARDPPARALPAR1LPAR5 | |
| SCHEMBL3579938 | 0.82 | MAPT (0.42) | CNR1EPHX2NR1H4LPAR1LPAR5 | |
| SCHEMBL3578978 | 0.82 | CNR1 (0.43) | CNR1EPHX2NR1H4LPAR1LPAR5 | |
| SCHEMBL3583628 | 0.81 | MCL1 (0.40) | CNR1 | |
| SCHEMBL12520790 | 0.81 | LPAR1 (0.47) | CNR1PPARGPPARDPPARAEPHX2 | |
| SCHEMBL3571214 | 0.80 | CNR1 (0.38) | CNR1LPAR1LPAR5SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |