⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29102107 | 0.65 | — | — | |
| SCHEMBL208780 | 0.62 | — | — | |
| SCHEMBL1444764 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL2859561 | 0.61 | — | — | |
| SCHEMBL15526286 | 0.60 | — | — | |
| SCHEMBL17734088 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL1275326 | 0.58 | — | — | |
| SCHEMBL16470963 | 0.57 | — | — | |
| SCHEMBL6557702 | 0.57 | — | — | |
| SCHEMBL17451017 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102838625-B | Tetrahydropyridothiazole compounds, preparation method thereof, pharmaceutical composition containing same and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-04-15 | — | — | CN | disclosed |
| CN-102838625-B | Tetrahydropyridothiazole compounds, preparation method thereof, pharmaceutical composition containing same and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-04-15 | — | — | CN | disclosed |
| CN-102838625-A | Tetrahydropyridothiazole compounds, preparation method thereof, pharmaceutical composition containing same and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-12-26 | — | — | CN | disclosed |
| CN-102838625-A | Tetrahydropyridothiazole compounds, preparation method thereof, pharmaceutical composition containing same and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-12-26 | — | — | CN | disclosed |
| US-20100292188-A1 | Compounds Comprising A Cyclobutoxy Group | UCB PHARMA S.A. (BE) | 2010-11-18 | — | — | US | disclosed |
| US-20100009969-A1 | Fused Oxazoles & Thiazoles As Histamine H3- Receptor Ligands | UCB PHARMA, S.A. (BE) | 2010-01-14 | — | — | US | disclosed |