Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.73 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.73 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | NEK2 | P51955 | 1/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414646 | 0.86 | EP300 (0.96) | EP300KAT2BKAT8CA2CHEK1 | |
| SCHEMBL8720110 | 0.85 | CHEK1 (0.65) | EP300KAT2BKAT8CA2CHEK1 | |
| SCHEMBL25971461 | 0.79 | EP300 (0.48) | EP300KAT2BKAT8CA2MCL1 | |
| SCHEMBL8026157 | 0.78 | GAA (0.55) | EP300KAT2BKAT8CA2MCL1 | |
| SCHEMBL4869305 | 0.77 | IDO1 (0.73) | EP300KAT2BKAT8CA2IDO1 | |
| SCHEMBL28327 | 0.77 | IDO1 (0.73) | EP300KAT2BKAT8CA2IDO1 | |
| SCHEMBL29351230 | 0.77 | IDO1 (0.73) | EP300KAT2BKAT8CA2IDO1 | |
| SCHEMBL30022761 | 0.76 | ALDH1A1 (0.52) | EP300KAT2BKAT8CA2MCL1 | |
| SCHEMBL5494774 | 0.76 | ALDH1A1 (0.52) | EP300KAT2BKAT8CA2MCL1 | |
| SCHEMBL134637 | 0.75 | EP300 (0.52) | EP300KAT2BKAT8CA2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2495245-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB Synthesis, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-2495245-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB Synthesis, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20100075945-A1 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | CHOI WOO-BAEG | 2010-03-25 | — | — | US | disclosed |
| US-20100075945-A1 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | CHOI WOO-BAEG | 2010-03-25 | — | — | US | disclosed |
| US-20100075945-A1 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | CHOI WOO-BAEG | 2010-03-25 | — | — | US | disclosed |
| US-7632828-B2 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632828-B2 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632828-B2 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1765821-A4 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS INC (US) | 2009-05-20 | — | — | EP | disclosed |
| EP-1765821-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB Synthesis, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060074070-A1 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. | 2006-04-06 | — | — | US | disclosed |
| WO-2005123069-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| US-6558956-B1 | Method and apparatus for detection of a controlled substance | THE UNIVERSITY OF WYOMING | 2003-05-06 | — | — | US | disclosed |
| WO-1998059234-A9 | METHOD AND APPARATUS FOR DETECTION OF A CONTROLLED SUBSTANCE | UNIV WYOMING (US) | 1999-04-15 | — | — | WO | disclosed |
| WO-1998059234-A1 | METHOD AND APPARATUS FOR DETECTION OF A CONTROLLED SUBSTANCE | THE UNIVERSITY OF WYOMING (US) | 1998-12-30 | — | — | WO | disclosed |
| US-3983048-A | Composition for accelerating oxygen removal comprised of a mixture of aqueous hydrazine and an aryl amine compound | OLIN CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074070-A1 | Gram-positive carbapenem antibacterials and processes for their preparation | MGAM, GSK3B, GSK3A | EP300 1791/4885KAT2B 2845/4885KAT8 2533/4885 |
| US-20100075945-A1 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | MGAM, GSK3B, GSK3A | EP300 1791/4885KAT2B 2845/4885KAT8 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.