Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.46 |
| ▸ | TLK2 | Q86UE8 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 4/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | KIF15 | Q9NS87 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584594 | 0.95 | PDPK1 (0.48) | PDPK1RAF1TLK2ALDH1A1CYP1A2 | |
| SCHEMBL3578296 | 0.93 | ALDH1A1 (0.46) | PDPK1RAF1TLK2ALDH1A1CYP1A2 | |
| SCHEMBL3582233 | 0.92 | RAF1 (0.46) | PDPK1RAF1TLK2ALDH1A1CYP1A2 | |
| SCHEMBL3584603 | 0.89 | MAP3K7 (0.46) | PDPK1RAF1TLK2ALDH1A1CYP1A2 | |
| SCHEMBL3575692 | 0.88 | MAP3K7 (0.47) | PDPK1RAF1TLK2ALDH1A1CYP1A2 | |
| SCHEMBL4759184 | 0.87 | AKT2 (0.43) | PDPK1ALDH1A1CYP1A2CYP3A4MAP3K7 | |
| SCHEMBL3578300 | 0.85 | ALDH1A1 (0.45) | PDPK1RAF1TLK2ALDH1A1CYP1A2 | |
| SCHEMBL3581636 | 0.84 | PDPK1 (0.43) | PDPK1RAF1TLK2AKT2NTRK1 | |
| SCHEMBL3575699 | 0.82 | MAP3K7 (0.46) | PDPK1RAF1TLK2ALDH1A1CYP1A2 | |
| SCHEMBL3572328 | 0.82 | PDPK1 (0.46) | PDPK1RAF1TLK2AKT2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902025-A1 | KINASE INHIBITORS | Allergan, Inc. (US) | 2008-03-26 | — | — | EP | claimed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | claimed |
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| US-20190008178-A1 | Process Recipe Cheese Product With Improved Melt And Firmness And Method For Manufacture | KRAFT FOODS GROUP BRANDS LLC | 2019-01-10 | — | — | US | disclosed |
| EP-2117334-B1 | FOOD COMPOSITIONS INCORPORATING ADDITIONAL LONG CHAIN FATTY ACIDS | MONSANTO TECHNOLOGY LLC (US) | 2018-11-14 | — | — | EP | disclosed |
| US-9376580-B2 | Use of oils with high concentrations of polyunsaturated fatty acids in plastics and surface coatings | MONSANTO TECHNOLOGY LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150275047-A1 | HIGH PUFA OILS FOR INDUSTRIAL APPLICATIONS | MONSANTO TECHNOLOGY LLC (US) | 2015-10-01 | — | — | US | disclosed |
| EP-2912130-A2 | HIGH PUFA OILS FOR INDUSTRIAL APPLICATIONS | Monsanto Technology LLC (US) | 2015-09-02 | — | — | EP | disclosed |
| US-8846781-B2 | Use of oils with high concentrations of polyunsaturated fatty acids in plastics and surface coatings | MONSANTO TECHNOLOGY LLC (US) | 2014-09-30 | — | — | US | disclosed |
| WO-2014066127-A2 | HIGH PUFA OILS FOR INDUSTRIAL APPLICATIONS | MONSANTO TECHNOLOGY LLC (US) | 2014-05-01 | — | — | WO | disclosed |
| US-7749530-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| WO-2010075197-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| EP-2197962-A1 | USE OF OILS WITH HIGH CONCENTRATIONS OF POLYUNSATURATED FATTY ACIDS IN PLASTICS AND SURFACE COATINGS | Monsanto Technology, LLC (US) | 2010-06-23 | — | — | EP | disclosed |
| US-7692005-B2 | Kinase inhibitors | ALLERGAN, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20090208557-A1 | Kinase inhibitors | ALLERGAN, INC. | 2009-08-20 | — | — | US | disclosed |
| WO-2009042770-A1 | USE OF OILS WITH HIGH CONCENTRATIONS OF POLYUNSATURATED FATTY ACIDS IN PLASTICS AND SURFACE COATINGS | MONSANTO TECHNOLOGY LLC (US) | 2009-04-02 | — | — | WO | disclosed |
| US-20090081465-A1 | USE OF OILS WITH HIGH CONCENTRATIONS OF POLYUNSATURATED FATTY ACIDS IN PLASTICS AND SURFACE COATINGS | MONSANTO TECHNOLOGY LLC (US) | 2009-03-26 | — | — | US | disclosed |
| EP-1902025-A1 | KINASE INHIBITORS | Allergan, Inc. (US) | 2008-03-26 | — | — | EP | disclosed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208557-A1 | Kinase inhibitors | PTK2, MAP3K6, MAP3K20 | PDPK1 82/4885RAF1 172/4885TLK2 304/4885 |
| US-20070032478-A1 | Kinase Inhibitors | ABL1, LCK, ERBB2 | PDPK1 86/4885RAF1 69/4885TLK2 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.