Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 5/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582651 | 0.99 | MPL (0.36) | MPLNISCHRARBCHKABRD4 | |
| SCHEMBL10153203 | 0.93 | RARB (0.38) | MPLRARBCHKAMCL1BRD4 | |
| SCHEMBL12821228 | 0.92 | MPL (0.33) | MPLNISCHRARBBRD4 | |
| SCHEMBL12822754 | 0.91 | CHKA (0.36) | MPLCHKA | |
| SCHEMBL12907934 | 0.90 | RARB (0.37) | MPLRARBCHKABRD4 | |
| SCHEMBL9015779 | 0.89 | RARB (0.33) | MPLRARBCHKAMCL1BRD4 | |
| SCHEMBL13674915 | 0.88 | MPL (0.34) | MPLNISCHRARBBRD4SLC5A1 | |
| SCHEMBL13264565 | 0.88 | MPL (0.34) | MPLNISCHRARBCHKABRD4 | |
| SCHEMBL13586379 | 0.87 | BRD4 (0.39) | MPLNISCHRARBCHKABRD4 | |
| SCHEMBL12907011 | 0.87 | BRD4 (0.33) | MPLRARBCHKABRD4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120097895-A1 | LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME | DIC CORPORATION (JP) | 2012-04-26 | — | — | US | disclosed |