Dimethylaminoethanol

Dimethylaminoethanol

SCHEMBL358310

CC(=O)O.CN(C)CCO

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Dimethylaminoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.71
FFAR3 O14843 1/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
PAOX Q6QHF9 1/20 0.39
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRM3 P20309 1/20 0.37
CHRNA4 P43681 1/20 0.37
DRD4 P21917 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
KDM4A O75164 7/20 0.33
KDM4C Q9H3R0 7/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 2/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylaminoethanol SCHEMBL1131226 0.91 MAPT (0.75) MAPTPAOXCHRM2CHRM4CHRM5
Dimethylaminoethanol SCHEMBL1131465 0.91 MAPT (0.75) MAPTPAOXCHRM2CHRM4CHRM5
Pyruvate SCHEMBL1131171 0.89 MAPT (0.63) MAPTPAOXCHRM2CHRM4CHRM5
Dimethylaminoethanol SCHEMBL1131507 0.88 MAPT (0.71) MAPTPAOXCHRM2CHRM4CHRM5
Dimethylaminoethanol SCHEMBL28732416 0.88 MAPT (0.55) MAPTFFAR3LCKFYNPAOX
Dimethylaminoethanol SCHEMBL28143875 0.86 MAPT (0.67) MAPTPAOXCHRM2CHRM4CHRM5
Dimethylaminoethanol SCHEMBL357520 0.86 MAPT (0.67) MAPTFFAR3PAOXCHRM2CHRM4
Methacrylic Acid SCHEMBL3423292 0.85 MAPT (0.57) MAPTPAOXCHRM2CHRM4CHRM5
Acetic Acid SCHEMBL27684197 0.84 FFAR3 (0.50) MAPTFFAR3LCKFYNPAOX
Acetic Acid SCHEMBL5526730 0.84 FFAR3 (0.50) MAPTFFAR3LCKFYNPAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160017540-A1 PRETREATMENT AND FRACTIONATION OF LIGNOCELLULOSIC BIOMASS SUGANIT SYSTEMS, INC. 2016-01-21 US claimed
EP-2971190-A1 ALKALINE TREATMENT OF LIGNOCELLULOSIC BIOMASS Suganit Systems, Inc. (US) 2016-01-20 EP claimed
US-9102647-B2 Method for preparing lactide using an ionic solvent HYUNDAI MOTOR COMPANY (KR) 2015-08-11 US claimed
WO-2014144588-A1 ALKALINE TREATMENT OF LIGNOCELLULOSIC BIOMASS SUGANIT SYSTEMS, INC. (US) 2014-09-18 WO claimed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US claimed
US-20140187798-A1 METHOD FOR PREPARING LACTIDE USING AN IONIC SOLVENT HYUNDAI MOTOR COMPANY (KR) 2014-07-03 US claimed
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP claimed
US-20120027661-A1 PROCESS AND REACTOR SYSTEM FOR PRODUCING AMMONIA USING IONIC LIQUIDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-02 US claimed
US-20120011886-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY 2012-01-19 US claimed
CN-102299325-A Ionothermal process of manganese lithium phosphate anode material 2011-12-28 CN claimed
CN-102299322-A Ion hot preparation method for lithium iron phosphate positive electrode material 2011-12-28 CN claimed
EP-1805131-B1 IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS INNOVIA FILMS LTD (GB) 2011-02-16 EP claimed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO claimed
US-20100155660-A1 MIXTURES OF AMMONIA AND IONIC LIQUIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US claimed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
EP-0859816-B1 ELECTRICALLY DEPOSITED COATING AGENT BASF COATINGS AG (DE) 2002-05-08 EP claimed
US-6200447-B1 ELECTRODEPOSITABLE COATING FORMULATION COMPRISING CATHODICALLY DEPOSITABLE BINDER SELECTED FROM ACID SALTS OF AMINO-CONTAINING RESINS, ORGANIC SOLVENTS, WATER, AND AN ORGANIC AMINE SALT NOT REACTIVE WITH BINDER BASF COATINGS AG (DE) 2001-03-13 US claimed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-4053329-A METHOD OF IMPROVING CORROSION RESISTANCE OF METAL SUBSTRATES BY PASSIVATING WITH AN ONIUM SALT-CONTAINING MATERIAL PPG INDUSTRIES, INC. (US) 1977-10-11 US disclosed
US-3935087-A Method for electrodeposition of self-crosslinking cationic compositions PPG INDUSTRIES, INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160017540-A1 PRETREATMENT AND FRACTIONATION OF LIGNOCELLULOSIC BIOMASS LCT, MGAM, ENGASE MAPT 3673/4885FFAR3 3137/4885LCK 3239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.