Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455031 | 0.98 | TSHR (0.72) | TSHRKCNJ1CA2KCNH2LOXL2 | |
| SCHEMBL9545598 | 0.98 | TSHR (0.72) | TSHRKCNJ1CA2KCNH2LOXL2 | |
| SCHEMBL10879042 | 0.98 | TSHR (0.72) | TSHRKCNJ1CA2KCNH2LOXL2 | |
| SCHEMBL378397 | 0.94 | TSHR (0.78) | TSHRKCNJ1CA2KCNH2LOXL2 | |
| SCHEMBL9317263 | 0.90 | TSHR (0.62) | TSHRKCNJ1CA2KCNH2EPHX1 | |
| SCHEMBL18913824 | 0.90 | TSHR (0.69) | TSHRKCNJ1KCNH2LOXL2ALDH1A1 | |
| SCHEMBL14040730 | 0.89 | TSHR (0.60) | TSHRKCNJ1CA2KCNH2LOXL2 | |
| SCHEMBL8503415 | 0.89 | TSHR (0.60) | TSHRKCNJ1CA2KCNH2ALDH1A1 | |
| SCHEMBL8503416 | 0.89 | TSHR (0.60) | TSHRKCNJ1CA2KCNH2ALDH1A1 | |
| SCHEMBL250473 | 0.86 | TSHR (1.00) | TSHRKCNJ1KCNH2LOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398168-B2 | Preparation method of a glycoside compound | SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) | 2025-08-26 | — | — | US | disclosed |
| EP-4140974-B1 | METHODS OF IRON CATALYZED C-H BOND AMINATION | VERSITECH LTD (CN) | 2025-05-14 | — | — | EP | disclosed |
| CN-119751869-A | Polymer, liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element | 武汉柔显科技股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-118955244-A | Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex | 延安大学 | 2024-11-15 | — | — | CN | disclosed |
| US-12098126-B2 | Methods of iron catalyzed C-H bond amination | VERSITECH LIMITED (CN) | 2024-09-24 | — | — | US | disclosed |
| US-20230121302-A1 | METHODS OF IRON CATALYZED C-H BOND AMINATION | VERSITECH LIMITED (CN) | 2023-04-20 | — | — | US | disclosed |
| EP-4140974-A1 | METHODS OF IRON CATALYZED C-H BOND AMINATION | The University of Hong Kong (HK) | 2023-03-01 | — | — | EP | disclosed |
| CN-115710210-A | Iron catalyzed amination of C-H bonds | 港大科桥有限公司 | 2023-02-24 | — | — | CN | disclosed |
| US-20220380399-A1 | PREPARATION METHOD OF A GLYCOSIDE COMPOUND | SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) | 2022-12-01 | — | — | US | disclosed |
| CN-110950781-A | Novel diamine, polyamic acid, and polyimide | 日产化学工业株式会社 | 2020-04-03 | — | — | CN | disclosed |
| US-4689341-A | Antiarrhythmic imidazoles | SCHERING A.G. (DE) | 1987-08-25 | — | — | US | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| EP-0206567-A2 | Compounds of formula [1,1'-biphenyl]-2-carboxylic acid, 2'-[[[(substituted)phenyl]-(substituted)amino]carbonyl]-, pharmaceutical compositions comprising the compounds, and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4613609-A | Antiarrhythmic imidazoliums | SCHERING A. G. (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4602023-A | Diphenic acid monoamides | WARNER-LAMBERT COMPANY (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |
| US-4581370-A | Antiarrhythmic imidazoliums | SCHERING A.G. (DE) | 1986-04-08 | — | — | US | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| EP-0131302-A2 | Imidazolium salts, intermediates thereto and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |
| US-4374061-A | ACTIVATION, AMINATION, AND DIAZOTIZATION OF A POLYSACCHARIDE FOLLOWED BY REACTION WITH A GLOBULIN; CHROMATOGRAPHY; SEPARATION OF GLYCOPROTEINS | CENTER FOR BLOOD RESEARCH, INC. (US) | 1983-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12098126-B2 | Methods of iron catalyzed C-H bond amination | FTH1, FECH, HCCS | TSHR 1353/4885KCNJ1 1210/4885CA2 1088/4885 |
| US-20230121302-A1 | METHODS OF IRON CATALYZED C-H BOND AMINATION | FTH1, FECH, HCCS | TSHR 1353/4885KCNJ1 1210/4885CA2 1088/4885 |
| US-12398168-B2 | Preparation method of a glycoside compound | GALE, ST6GAL1, MGAM | TSHR 3818/4885KCNJ1 2014/4885CA2 1160/4885 |
| US-20220380399-A1 | PREPARATION METHOD OF A GLYCOSIDE COMPOUND | GALE, ST6GAL1, MGAM | TSHR 3818/4885KCNJ1 2014/4885CA2 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.