Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583255 | 1.00 | SIRT2 (0.37) | SIRT2ATML3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL15310409 | 0.90 | SIRT2 (0.37) | SIRT2ATML3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL3301977 | 0.90 | SIRT2 (0.37) | SIRT2ATML3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL3298164 | 0.88 | SIRT2 (0.37) | SIRT2ATML3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL3298161 | 0.88 | SIRT2 (0.37) | SIRT2ATML3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL3583777 | 0.83 | SIRT2 (0.37) | SIRT2ATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4416807 | 0.82 | RXFP1 (0.34) | SIRT2ATML3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL4336660 | 0.82 | RXFP1 (0.34) | SIRT2ATML3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL3301987 | 0.81 | ATM (0.36) | SIRT2ATML3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL3301980 | 0.81 | ATM (0.36) | SIRT2ATML3MBTL1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053038-B1 | AMINO ALCOHOL DERIVATIVE AND IMMUNOSUPPRESSIVE AGENT HAVING SAME AS AN ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2016-10-05 | — | — | EP | disclosed |
| US-8273748-B2 | Amino alcohol derivative and immunosuppresive agent having same as an active ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-8232319-B2 | Amino phosphate derivative and S1P receptor modulator having same as an active ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2012-07-31 | — | — | US | disclosed |
| US-20100010000-A1 | AMINO ALCOHOL DERIVATIVE AND IMMUNOSUPPRESIVE AGENT HAVING SAME AS AN ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20090325907-A1 | AMINO PHOSPHATE DERIVATIVE AND S1P RECEPTOR MODULATOR HAVING SAME AS AN ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2058317-A1 | AMINOPHOSPHORIC ACID ESTER DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-2053038-A1 | AMINOALCOHOL DERIVATIVE AND IMMUNOSUPPRESSANT CONTAINING THE SAME AS AN ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325907-A1 | AMINO PHOSPHATE DERIVATIVE AND S1P RECEPTOR MODULATOR HAVING SAME AS AN ACTIVE INGREDIENT | S1PR1, S1PR2, S1PR5 | SIRT2 2716/4885ATM 1772/4885L3MBTL1 4576/4885 |
| US-20100010000-A1 | AMINO ALCOHOL DERIVATIVE AND IMMUNOSUPPRESIVE AGENT HAVING SAME AS AN ACTIVE INGREDIENT | ALDH7A1, AADAT, IDO1 | SIRT2 2251/4885ATM 1489/4885L3MBTL1 3920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.