SCHEMBL3583437

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3588381	0.86	TTR (0.45)	TTRERN1COMTFTOGPR35
	SCHEMBL1447372	0.83	TTR (0.43)	TTRCOMTGPR35KDM4EALDH1A1
	SCHEMBL3582149	0.83	COMT (0.49)	TTRCOMTMAPT
	SCHEMBL1447359	0.83	COMT (0.49)	TTRCOMTMAPT
	SCHEMBL3587348	0.82	TTR (0.45)	TTRERN1COMTFTOGPR35
	SCHEMBL3587928	0.81	TTR (0.43)	TTRERN1COMTGPR35KDM4E
	SCHEMBL3587085	0.80	CRHBP (0.48)	TTRERN1GPR35KDM4EALDH1A1
	SCHEMBL3939794	0.79	TTR (0.39)	TTRERN1COMTFTOGPR35
	SCHEMBL3585962	0.79	TTR (0.43)	TTRERN1COMTFTOGPR35
	SCHEMBL1447055	0.78	TTR (0.40)	TTRERN1COMTGPR35KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.