⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637521 | 0.81 | — | — | |
| SCHEMBL13727797 | 0.81 | — | — | |
| SCHEMBL3364318 | 0.80 | — | — | |
| SCHEMBL5764124 | 0.79 | NOS3 (0.41) | — | |
| SCHEMBL29637542 | 0.77 | — | — | |
| SCHEMBL331515 | 0.77 | — | — | |
| SCHEMBL20772455 | 0.77 | — | — | |
| SCHEMBL29849906 | 0.77 | — | — | |
| SCHEMBL19532038 | 0.77 | NOS3 (0.47) | — | |
| Hydrochloric Acid SCHEMBL7051400 | 0.75 | NOS3 (0.95) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 631 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698583-A | A kind of preparation method of imidazopyridine derivatives | 湖南华腾制药有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-104163790-B | A kind of preparation technology of 2-amino-4-methyl-5 bromopyridine | GUIZHOU WYLTON JINGLIN ELECTRONIC MATERIAL CORP. (CN) | 2016-02-10 | — | — | CN | claimed |
| CN-104163790-A | Preparation technique of 2-amino-4-methyl-5-bromopyridine | GUIZHOU WYLTON JINGLIN ELECTRONIC MATERIAL CORP | 2014-11-26 | — | — | CN | claimed |
| CN-102321016-B | Synthesis method of 5-bromo-2-methyl hydroxypyridinecarboxylate | SHANDONG INST LIGHT INDUSTRY | 2013-04-10 | — | — | CN | claimed |
| CN-101863830-B | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2012-07-25 | — | — | CN | claimed |
| CN-102321016-A | Synthesis method of 5-bromo-2-methyl 4-hydroxypyridinecarboxylate | SHANDONG INST LIGHT INDUSTRY | 2012-01-18 | — | — | CN | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| CN-101863830-A | Synthesis method of 2-amino-5-bromine isonicotinic acid | ZHEJIANG CHIMICA LAB CO LTD | 2010-10-20 | — | — | CN | claimed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |
| WO-2003013523-A1 | SH3 PROTEIN DOMAINS AND THEIR LIGANDS | ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) | 2003-02-20 | — | — | WO | claimed |
| US-5972975-A | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | claimed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | claimed |
| WO-2026102082-A1 | ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-20260132119-A1 | Alkylphenyl Substituted Compounds, Compositions and Methods of Use | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-14 | — | — | US | disclosed |
| EP-4178620-B1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-04-01 | — | — | EP | disclosed |
| CN-121426741-A | Synthesis method of 2- (5-bromo-2- ((tert-butoxycarbonyl) amino) pyridin-4-yl) acetic acid tert-butyl ester | 上海毕得医药科技股份有限公司 | 2026-01-30 | — | — | CN | disclosed |
| EP-0652875-A1 | (HETERO)-ARYL KETONES DERIVATIVES WITH ANTIBACTERIAL PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 1995-05-17 | — | — | EP | disclosed |
| US-5290943-A | Halogenation of pyridine compound | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| WO-1994002478-A1 | (HETERO)-ARYL KETONES DERIVATIVES WITH ANTIBACTERIAL PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 1994-02-03 | — | — | WO | disclosed |
| EP-0530524-A1 | Method of producing 2-amino-3-nitro-5-halogenopyridine | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |