SCHEMBL35843124

SCHEMBL35843124

CCOC(=O)CCc1cc(O)ccc1-c1ccc(-c2cccc(C(F)(F)F)c2)c(C(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
GRIN1 Q05586 2/20 0.38
GRIN2B Q13224 2/20 0.38
AKR1C3 P42330 2/20 0.37
AKR1C2 P52895 2/20 0.37
MCL1 Q07820 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
XPO1 O14980 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
KIFC1 Q9BW19 2/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1812098 1.00 KDM4E (0.43) KDM4EMEN1MAPTKMT2AGRIN1
SCHEMBL1906562 0.89 MTNR1A (0.41) KDM4EMEN1MAPTKMT2AAKR1C3
SCHEMBL1891473 0.89 CYP4F2 (0.39) KDM4EAKR1C3AKR1C2CYP4F2CYP4A11
SCHEMBL35843123 0.89 CYP4F2 (0.39) KDM4EAKR1C3AKR1C2CYP4F2CYP4A11
SCHEMBL1887566 0.89 KDM4E (0.46) KDM4EMEN1MAPTKMT2AGRIN1
SCHEMBL38660151 0.89 KDM4E (0.46) KDM4EMEN1MAPTKMT2AGRIN1
SCHEMBL38660721 0.88 CYP4F2 (0.46) KDM4EMEN1MAPTKMT2AGRIN1
SCHEMBL1895417 0.88 CYP4F2 (0.46) KDM4EMEN1MAPTKMT2AGRIN1
SCHEMBL1810928 0.88 KDM4E (0.45) KDM4EMEN1MAPTKMT2AGRIN1
SCHEMBL35843126 0.86 MME (0.42) MAPTAKR1C3AKR1C2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099533-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) WITH GPBP1 INHIBITORS UNIVERSITAT DE VALÈNCIA (ES) 2026-05-15 WO disclosed