Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 6/20 | 0.33 |
| ▸ | CPT2 | P23786 | 4/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584110 | 0.86 | IRAK4 (0.34) | CPT1ACPT2IRAK4CPT1BSHMT1 | |
| SCHEMBL3583234 | 0.86 | CPT1A (0.35) | CPT1ACPT2IRAK4CPT1BLMNA | |
| SCHEMBL13031262 | 0.85 | NPY5R (0.35) | KCNH2 | |
| SCHEMBL3587157 | 0.85 | CXCR3 (0.41) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL3581627 | 0.84 | IRAK4 (0.33) | CPT1ACPT2IRAK4CPT1BKCNH2 | |
| SCHEMBL3576143 | 0.84 | CXCR3 (0.36) | CPT1ACPT2IRAK4KCNH2 | |
| SCHEMBL3583237 | 0.84 | CPT1A (0.34) | CPT1ACPT2IRAK4CPT1BLMNA | |
| SCHEMBL3581779 | 0.84 | TLR9 (0.34) | CPT1ACPT2IRAK4CPT1BKCNH2 | |
| SCHEMBL3588834 | 0.83 | GRIN1 (0.35) | CPT1ACPT2IRAK4CPT1BLMNA | |
| SCHEMBL3590320 | 0.83 | IRAK4 (0.33) | CPT1ACPT2IRAK4CPT1BSHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642634-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-04 | — | — | US | claimed |
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | claimed |
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | CPT1A 1947/4885CPT2 2552/4885IRAK4 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.