Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5304451 | 0.85 | DPP4 (0.52) | DPP4CYP3A4 | |
| SCHEMBL3586023 | 0.82 | DPP4 (0.47) | DPP4DPP8CYP3A4 | |
| SCHEMBL5034640 | 0.81 | DPP4 (0.52) | DPP4CYP3A4 | |
| SCHEMBL6508227 | 0.79 | DPP4 (0.54) | DPP4CYP3A4 | |
| SCHEMBL6507784 | 0.77 | DPP4 (0.59) | DPP4 | |
| SCHEMBL6426896 | 0.77 | DPP4 (0.55) | DPP4CYP3A4 | |
| SCHEMBL6511158 | 0.77 | DPP4 (0.56) | DPP4 | |
| SCHEMBL3392452 | 0.72 | DPP4 (1.00) | DPP4DPP8CYP3A4 | |
| SCHEMBL8229034 | 0.72 | DPP4 (1.00) | DPP4DPP8CYP3A4 | |
| SCHEMBL5032330 | 0.72 | DPP4 (1.00) | DPP4DPP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790736-B2 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-07 | — | — | US | claimed |
| EP-1506967-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2007-11-21 | — | — | EP | claimed |
| EP-1506967-A1 | Dipeptidyl peptidase inhibitors | Syrrx, Inc. (US) | 2005-02-16 | — | — | EP | claimed |
| EP-1911754-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2013-10-09 | — | — | EP | disclosed |
| EP-1911754-A1 | Dipeptidyl peptidase inhibitors | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| EP-1506967-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2007-11-21 | — | — | EP | disclosed |
| EP-1506967-A1 | Dipeptidyl peptidase inhibitors | Syrrx, Inc. (US) | 2005-02-16 | — | — | EP | disclosed |