SCHEMBL358606

SCHEMBL358606

Cc1ccc(CO)c(C)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 3/20 0.43
CD274 Q9NZQ7 3/20 0.43
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 1/20 0.36
TSHR P16473 1/20 0.36
SHBG P04278 1/20 0.35
TRPA1 O75762 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
METAP2 P50579 1/20 0.31
TDP2 O95551 1/20 0.31
NSD2 O96028 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PAX8 Q06710 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
KLF10 Q13118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL3840466 0.97 PDCD1 (0.42) PDCD1CD274CYP1A2CYP2A6TSHR
Ammonia Solution, Strong SCHEMBL439692 0.97 PDCD1 (0.42) PDCD1CD274CYP1A2CYP2A6TSHR
Ammonia Solution, Strong SCHEMBL27888422 0.95 PDCD1 (0.41) PDCD1CD274CYP1A2CYP2A6TSHR
SCHEMBL13199168 0.89 PDCD1 (0.50) PDCD1CD274CYP2A6TSHRSHBG
Bicarbonate SCHEMBL16179255 0.87 PDCD1 (0.36) PDCD1CD274SMN1; SMN2METAP2GLA
SCHEMBL15957639 0.80 PDCD1 (0.41) PDCD1CD274CYP1A2CYP2A6SHBG
SCHEMBL27362377 0.80 SHBG (0.42) PDCD1CD274CYP1A2CYP2A6TSHR
SCHEMBL26606750 0.80 TDP1 (0.32) TRPA1ATMSMN1; SMN2
SCHEMBL205613 0.80 PDCD1 (0.36) PDCD1CD274CYP1A2CYP2A6TSHR
SCHEMBL2211047 0.78 POLB (0.50) PDCD1CD274TSHRSHBGSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082208-B Adsorption separation method of cymene oxidation product 山东新和成精化科技有限公司 2025-05-09 CN claimed
US-7576170-B2 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS (US) 2009-08-18 US claimed
EP-4688952-A1 POLYMER COMPOSITION WITH FLAME AND ELECTRICAL TRACKING RESISTANCE Celanese International Corporation (US) 2026-02-11 EP disclosed
CN-116082208-B Adsorption separation method of cymene oxidation product 山东新和成精化科技有限公司 2025-05-09 CN disclosed
WO-2024211672-A1 POLYMER COMPOSITION WITH FLAME AND ELECTRICAL TRACKING RESISTANCE CELANESE INTERNATIONAL CORPORATION (US) 2024-10-10 WO disclosed
CN-113387055-B Film, method for producing film, and bag 住友化学株式会社 2024-06-07 CN disclosed
WO-2024086642-A1 ENHANCED YEASTICIDAL EFFICACY OF LACTIC ACID BASED ANTIMICROBIAL HANDWASH ECOLAB USA INC. (US) 2024-04-25 WO disclosed
CN-117425653-A Method for producing bipyridine derivative, method for producing macrocyclic compound, method for producing metal complex containing macrocyclic compound as ligand, metal complex, electrode for air battery, and air battery 住友化学株式会社 2024-01-19 CN disclosed
WO-2023237568-A1 PROCESS AND APPARATUS FOR TREATING METHANE-CONTAINING GAS HITACHI ZOSEN INOVA AG (CH) 2023-12-14 WO disclosed
CN-116082208-A Adsorption separation method of cymene oxidation product 山东新和成维生素有限公司 2023-05-09 CN disclosed
US-11643533-B2 Film, method of producing film, and bag SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-09 US disclosed
EP-0422508-A2 Liquid detergent composition KAO CORPORATION (JP) 1991-04-17 EP disclosed
US-4537720-A N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamino)-4-oxo-azetidines and process ELI LILLY AND COMPANY (US) 1985-08-27 US disclosed
US-4477660-A 7-(S)-Acylaminocephalosporin sulfones and process ELI LILLY AND COMPANY (US) 1984-10-16 US disclosed
US-4474879-A Process for 3-hydroxymethyl cephalosporin sulfones ELI LILLY AND COMPANY (US) 1984-10-02 US disclosed
US-4459405-A Desacetylcephalosporin sulfones ELI LILLY AND COMPANY (US) 1984-07-10 US disclosed
EP-0109816-A1 N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process ELI LILLY AND COMPANY (US) 1984-05-30 EP disclosed
EP-0109301-A2 7-(S)-acylaminocephalosporin sulfones and process ELI LILLY AND COMPANY (US) 1984-05-23 EP disclosed
EP-0109300-A2 Desacetylcephalosporin sulfones ELI LILLY AND COMPANY (US) 1984-05-23 EP disclosed
US-4436596-A N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process ELI LILLY AND COMPANY (US) 1984-03-13 US disclosed