SCHEMBL3586419

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3583841	0.87	MAPT (0.39)	MAPTKDM4ETTRCOMTGPR35
	SCHEMBL3591192	0.87	TTR (0.39)	MAPTKDM4ETTRCOMTGPR35
	SCHEMBL3581810	0.86	MAPT (0.38)	MAPTKDM4ETTRCOMTGPR35
	SCHEMBL3586245	0.85	TTR (0.38)	MAPTKDM4ETTRCOMTGPR35
	SCHEMBL1447358	0.85	COMT (0.37)	MAPTKDM4ETTRCOMTGPR35
	SCHEMBL3587064	0.83	TTR (0.39)	MAPTKDM4ETTRCOMTGPR35
	SCHEMBL3589662	0.82	COMT (0.52)	MAPTKDM4ETTRCOMTRARB
	SCHEMBL3586941	0.82	EIF4E (0.42)	MAPTKDM4ETHRBMAOAMAOB
	SCHEMBL1447164	0.82	CRHBP (0.40)	MAPTKDM4ETTRCOMTGPR35
	SCHEMBL3588938	0.81	MAPT (0.37)	MAPTKDM4ETTRCOMTGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.