Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3581043 | 0.90 | IRAK4 (0.36) | IRAK4 | |
| SCHEMBL13031178 | 0.86 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL3596525 | 0.85 | CPT1A (0.33) | IRAK4 | |
| SCHEMBL3576143 | 0.80 | CXCR3 (0.36) | IRAK4 | |
| SCHEMBL3581627 | 0.80 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL3588152 | 0.80 | CXCR3 (0.38) | IRAK4 | |
| SCHEMBL3591790 | 0.80 | PSEN1 (0.36) | IRAK4 | |
| SCHEMBL3584110 | 0.79 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL3588834 | 0.79 | GRIN1 (0.35) | IRAK4 | |
| SCHEMBL3590320 | 0.79 | IRAK4 (0.33) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642634-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-04 | — | — | US | claimed |
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | IRAK4 367/4885FLT3 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.