Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL554509 | 0.82 | MAOA (0.55) | MAOAMAOBHRH1ALDH1A1MAPK1 | |
| SCHEMBL14223692 | 0.82 | MAOA (0.50) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL3441777 | 0.80 | MAOA (0.61) | MAOAMAOBHTR2AALDH1A1MAPK1 | |
| SCHEMBL10798872 | 0.80 | MAOA (0.47) | MAOAMAOBHRH1HTR2AALDH1A1 | |
| SCHEMBL26648419 | 0.79 | MAOA (0.60) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL14223690 | 0.79 | MAOA (0.60) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| Hydrochloric Acid SCHEMBL10795186 | 0.79 | MAOA (0.46) | MAOAMAOBHRH1HTR2AALDH1A1 | |
| SCHEMBL376197 | 0.78 | MAOA (0.50) | MAOAMAOBHRH1HTR2AALDH1A1 | |
| SCHEMBL13269950 | 0.76 | MAOA (0.56) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL3590718 | 0.75 | HTR2A (0.44) | MAOAHRH1HTR2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | Wurster, Siegfried (FI) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | SSTR1, SSTR4, SSTR3 | MAOA 3631/4885MAOB 2725/4885HRH1 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.