Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28241687 | 1.00 | TDP1 (0.67) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL8850998 | 1.00 | TDP1 (0.67) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL21828462 | 1.00 | TDP1 (0.67) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL49092 | 1.00 | TDP1 (0.67) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL36041 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL27725301 | 0.97 | TDP1 (0.62) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL5153430 | 0.97 | TDP1 (0.62) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL27695057 | 0.97 | TDP1 (0.62) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL28810431 | 0.94 | TDP1 (0.59) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL11062962 | 0.94 | TDP1 (0.59) | TDP1FFAR3LCKFYNOR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102395388-B | Production of moldable bone substitutes | PROMIMIC AB (SE) | 2016-03-09 | — | — | CN | claimed |
| US-20130266643-A1 | Compositions comprising glyceryl-triacetate (GTA) and uses in human performance optimization and thermogenesis | HPO LIFE SCIENCES INC (US) | 2013-10-10 | — | — | US | claimed |
| CN-102395388-A | Production of moldable bone substitutes | PROMIMIC AB | 2012-03-28 | — | — | CN | claimed |
| EP-0092993-B1 | COMPOSITION FOR INVESTIGATING ALIMENTARY FUNCTIONS | A/S Alfred Benzon (DK) | 1989-03-01 | — | — | EP | claimed |
| WO-1983003762-A1 | COMPOSITION AND METHOD FOR INVESTIGATING ALIMENTARY FUNCTIONS | A/S ALFRED BENZON (DK) | 1983-11-10 | — | — | WO | claimed |
| EP-0092993-A2 | Composition for investigating alimentary functions | A/S Alfred Benzon (DK) | 1983-11-02 | — | — | EP | claimed |
| CN-118369306-A | Enol ether pro-fragrances | 弗门尼舍有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-118302402-A | Process for the preparation of cyclic dienes | 弗门尼舍有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118251207-A | Fragrance composition with moisturizing benefit | 弗门尼舍有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118215656-A | Cyclic acetals and ketals for photoinduction-released active aldehydes and ketones | 弗门尼舍有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113873884-B | Arthropod control composition | 弗门尼舍有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-114794101-B | Antimicrobial compositions | 弗门尼舍有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-111183136-B | Amber odorant | 弗门尼舍有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2006089843-A2 | ANTI-MISUSE MICROPARTICULATE ORAL DRUG FORM | FLAMEL TECHNOLOGIES (FR) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006087395-A1 | MULTIMICROPARTICULATE ORAL PHARMACEUTICAL FORM WITH MODIFIED RELEASE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | FLAMEL TECHNOLOGIES (FR) | 2006-08-24 | — | — | WO | disclosed |
| WO-2006087394-A1 | ORAL PHARMACEUTICAL FOR OF LOSARTAN | FLAMEL TECHNOLOGIES (FR) | 2006-08-24 | — | — | WO | disclosed |
| US-6235312-B1 | MONOGLYCERIDES WITH ACYL GROUPS WITH WATER | EASTMAN CHEMICAL COMPANY | 2001-05-22 | — | — | US | disclosed |
| EP-0266199-B2 | Liquid cleaning products | UNILEVER PLC (GB) | 2000-02-09 | — | — | EP | disclosed |
| CN-1048861-A | What contain disordered structure starch is the blend compositions of base-material with the polymkeric substance | WARNER LAMBERT CO (US) | 1991-01-30 | — | — | CN | disclosed |
| EP-0092993-B1 | COMPOSITION FOR INVESTIGATING ALIMENTARY FUNCTIONS | A/S Alfred Benzon (DK) | 1989-03-01 | — | — | EP | disclosed |