Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28241687 | 1.00 | TDP1 (0.67) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL8850998 | 1.00 | TDP1 (0.67) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL358822 | 1.00 | TDP1 (0.67) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL21828462 | 1.00 | TDP1 (0.67) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL36041 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL27725301 | 0.97 | TDP1 (0.62) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL5153430 | 0.97 | TDP1 (0.62) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL27695057 | 0.97 | TDP1 (0.62) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL28810431 | 0.94 | TDP1 (0.59) | TDP1FFAR3LCKFYNOR51E2 | |
| Propylene Glycol SCHEMBL11062962 | 0.94 | TDP1 (0.59) | TDP1FFAR3LCKFYNOR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15694 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079934-A | Pinonic acid modified epoxy resin, preparation method thereof, extremely applicable high-elasticity low-temperature-resistant anticorrosive paint, preparation method thereof and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094997-A | Aqueous polyurethane coatings for printing applications | — | 2026-05-26 | — | — | CN | claimed |
| US-12637584-B2 | Waterborne polyurethane-epoxy resin based primer composition and its preparation method thereof | BASF COATINGS GMBH (DE) | 2026-05-26 | — | — | US | claimed |
| CN-120137518-B | Yellowing-resistant paint for cement-based floor finish and application method thereof | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-117534431-B | Low-carbon slag cement and preparation method thereof | 安徽海螺材料科技股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060389-A | Water-based anti-icing paint and preparation method and application thereof | 天津灯塔涂料工业发展有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-12631965-B2 | Positive photosensitive resin composition for low-temperature process and method for preparing photoresist film | ECHEM SOLUTIONS CORP. (TW) | 2026-05-19 | — | — | US | claimed |
| CN-122060365-A | Low-gloss high-sewage-resistance woodenware white finish paint and preparation method thereof | 广州立邦涂料有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-118291025-B | Water-based wind power blade finishing paint with excellent alkali resistance and weather resistance and preparation method thereof | 厦门双瑞船舶涂料有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037758-A | Water-based matte antibacterial light-absorbing coating and preparation method thereof | 广东绿色大地化工有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-0349301-A2 | Positive-type photoresist composition | MITSUBISHI KASEI CORPORATION (JP) | 1990-01-03 | — | — | EP | claimed |
| EP-0324579-A2 | Foundry moulding composition | BORDEN (UK) LIMITED (GB) | 1989-07-19 | — | — | EP | claimed |
| US-4849227-A | Pharmaceutical compositions | EURASIAM LABORATORIES, INC. (US) | 1989-07-18 | — | — | US | claimed |
| EP-0302065-A1 | PHARMACEUTICAL COMPOSITIONS. | EURASIAM LAB (US) | 1989-02-08 | — | — | EP | claimed |
| US-4802890-A | MIXTURE OF COAL; PHENOL-FORMALDEHYDE RESOLES; ESTER CURING AGENT; ALKALINE SOLUTION; DRYING | FOSROC INTERNATIONAL LIMITED (GB) | 1989-02-07 | — | — | US | claimed |
| CN-87103560-A | Pharmaceutical composition | — | 1988-05-18 | — | — | CN | claimed |
| EP-0241156-A2 | Agglomeration of coal fines | FOSROC INTERNATIONAL LIMITED (GB) | 1987-10-14 | — | — | EP | claimed |
| WO-1987005505-A1 | PHARMACEUTICAL COMPOSITIONS | EURASIAM LABORATORIES, INC. (US) | 1987-09-24 | — | — | WO | claimed |
| US-4158008-A | BASIC DECARBOXYLATION OF PROPYLENE GLYCOL ESTERS IN A HIGH BOILING SOLVENT | BASF AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | claimed |
| US-RE29201-E | Production of alkoxy phenolic compounds | CPC INTERNATIONAL INC. (US) | 1977-05-03 | — | — | US | claimed |