Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | IL1B | P01584 | 2/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31170846 | 0.81 | CRBN (0.44) | CRBNCYP11B1CYP11B2DDB1KMT2A | |
| SCHEMBL3588406 | 0.80 | CRBN (0.42) | CRBNCYP11B1CYP11B2DDB1KMT2A | |
| SCHEMBL3593120 | 0.73 | CRBN (0.42) | CRBNCYP11B1CYP11B2DDB1KMT2A | |
| SCHEMBL2629391 | 0.72 | EPHX2 (0.54) | CRBNCYP11B1CYP11B2KMT2AMEN1 | |
| SCHEMBL3587267 | 0.71 | BRD4 (0.54) | CRBNDDB1KMT2AMEN1BRD4 | |
| SCHEMBL3606359 | 0.70 | PDK2 (0.36) | CRBNDDB1ADRA2CKMT2AMEN1 | |
| SCHEMBL9025184 | 0.69 | CASP3 (0.46) | CRBNCYP11B1CYP11B2KMT2AMEN1 | |
| SCHEMBL1716064 | 0.68 | SLC6A2 (0.38) | CRBNDDB1ADRA2CKMT2AMEN1 | |
| SCHEMBL3600186 | 0.67 | CA9 (0.47) | CRBNCYP11B1CYP11B2DDB1KMT2A | |
| SCHEMBL3588988 | 0.67 | CYP11B1 (0.53) | CRBNCYP11B1CYP11B2DDB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | CRBN 762/4885CYP11B1 162/4885CYP11B2 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.