Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448230 | 1.00 | HTT (0.70) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| Water SCHEMBL28126820 | 0.98 | HTT (0.68) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL20292903 | 0.98 | HTT (0.68) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL9376922 | 0.85 | HTT (0.53) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL9274000 | 0.84 | NPC1 (0.78) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL440439 | 0.83 | HTT (1.00) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL29361503 | 0.83 | HTT (1.00) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL28328610 | 0.81 | HTT (0.49) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| Quinoline SCHEMBL28218277 | 0.80 | ALDH1A1 (0.63) | HTTCYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL28242830 | 0.80 | NPC1 (0.67) | HTTCYP1A2CYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120887867-B | Quinoline biaryl heterocycle PI3K/HDAC double-target small molecule inhibitor and application thereof | 浙江中医药大学 | 2026-05-15 | — | — | CN | claimed |
| CN-119775203-A | Synthesis method of carbamazepine intermediate 6- (3, 3-diethoxypropyl) quinoline | 河北科技大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119331601-A | Preparation and application methods of room-temperature phosphorescent material based on octatomic cucurbituril and 6-bromoisoquinoline derivatives | 贵州大学 | 2025-01-21 | — | — | CN | claimed |
| CN-116283760-B | Preparation method of 6-bromoquinoline | 安徽英特美科技有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-117865883-A | Preparation method of 6-bromoquinoline | 常州琦诺生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-116947753-A | Method for synthesizing monofluoroalkylated aromatic hydrocarbon compound by adopting direct fluorination method | 郑州泰基鸿诺医药股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-113896732-B | Preparation method and application of anticancer drug carbamatinib | 沈阳红旗制药有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116554211-A | Blue fluorescent material based on fluoroborobiquinoline complex, and preparation method and application thereof | 东南大学 | 2023-08-08 | — | — | CN | claimed |
| CN-116283760-A | Preparation method of 6-bromoquinoline | 安徽英特美科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116217478-A | Synthesis method of 6-amino-3-difluoromethyl quinoline | 苏州康润医药有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-106432073-B | A kind of preparation method of the bromo- 4- chloroquinoline of 6- | 上海再启生物技术有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-108148055-A | A kind of D- π-A types organic fluorescence materials and preparation method based on naphthalene | 陕西师范大学 | 2018-06-12 | — | — | CN | claimed |
| CN-106432073-A | 6-bromo-4-chloroquinoline preparation method | 上海再启生物技术有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-105906562-A | High-purity 2-(3, 5-dimethylphenyl)-6-isobutyl quinoline synthesis method | 上海华显新材料科技有限公司 | 2016-08-31 | — | — | CN | claimed |
| CN-105837503-A | Preparation method for 6-bromine quinoline | 蚌埠中实化学技术有限公司 | 2016-08-10 | — | — | CN | claimed |
| CN-105753838-A | Novel high-regioselectivity amination method of quinoline derivatives | 安阳师范学院 | 2016-07-13 | — | — | CN | claimed |
| EP-1399458-B1 | AN ARYLATION METHOD FOR THE FUNCTIONALIZATION OF O-ALLYL ERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2005-08-03 | — | — | EP | claimed |
| US-6841680-B2 | N-type calcium channel antagonists for the treatment of pain | ASTRAZENECA AB (SE) | 2005-01-11 | — | — | US | claimed |
| EP-0365863-B1 | Novel quinolyloxazole-2-ones useful as proteinkinase C inhibitors | MERRELL DOW PHARMA (US) | 1994-08-17 | — | — | EP | claimed |
| CN-1043717-A | Cephalosporin compound | TANABE SEIYAKU CO (JP) | 1990-07-11 | — | — | CN | claimed |