Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101926 | 0.84 | ALDH1A1 (0.64) | MAPTGAAALDH1A1KDM4EPTK2B | |
| SCHEMBL21388627 | 0.81 | MAPT (0.60) | MAPTGAAALDH1A1KDM4EPTK2B | |
| SCHEMBL15247281 | 0.81 | MAPT (0.55) | MAPTGAAALDH1A1KDM4EPTK2B | |
| SCHEMBL18509241 | 0.81 | MAPT (0.55) | MAPTGAAALDH1A1KDM4EPTK2B | |
| SCHEMBL14146896 | 0.81 | MAPT (0.60) | MAPTGAAALDH1A1KDM4EPTK2B | |
| SCHEMBL20354340 | 0.81 | ALDH1A1 (0.55) | MAPTGAAALDH1A1KDM4EPTK2B | |
| SCHEMBL2427568 | 0.81 | MAPT (0.60) | MAPTGAAALDH1A1KDM4EPTK2B | |
| Hydrochloric Acid SCHEMBL2426774 | 0.79 | MAPT (0.58) | MAPTGAAALDH1A1KDM4EPTK2B | |
| Hydrochloric Acid SCHEMBL21378535 | 0.79 | MAPT (0.58) | MAPTGAAALDH1A1KDM4EPTK2B | |
| Hydrochloric Acid SCHEMBL21378536 | 0.79 | MAPT (0.58) | MAPTGAAALDH1A1KDM4EPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102834380-A | Inhibitors of protein kinases | INGENIUM PHARMACEUTICALS GMBH | 2012-12-19 | — | — | CN | disclosed |
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | LCK, ZAP70, FYN | MAPT 2260/4885GAA 3549/4885ALDH1A1 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.