Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044795 | 0.89 | GAA (0.55) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL5703485 | 0.84 | GAA (0.58) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL6906441 | 0.83 | GAA (0.57) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL6906447 | 0.83 | GAA (0.60) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL13369363 | 0.83 | GAA (0.48) | GAAMAPTALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL6313355 | 0.83 | GAA (0.57) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11347038 | 0.82 | GAA (0.52) | GAAMAPTTP53GLACDK1 | |
| Ethoxysulfuron SCHEMBL29386240 | 0.82 | GAA (0.53) | GAAMAPTTP53GLARXFP1 | |
| Ethoxysulfuron SCHEMBL65311 | 0.82 | GAA (0.53) | GAAMAPTTP53GLARXFP1 | |
| Ethoxysulfuron SCHEMBL2323273 | 0.81 | GAA (0.52) | GAAMAPTTP53GLARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20050004123-A1 | Substituted aryl sulphonyl(thio)ureas used as herbicides | BAYER AG (DE) | 2005-01-06 | — | — | US | disclosed |
| US-6838414-B2 | Substituted aryl sulphonyl(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20030153463-A1 | Substituted aryl sulphonyl(thio)ureas | GESING ERNST RUDOLF F (DE) | 2003-08-14 | — | — | US | disclosed |
| US-6451737-B1 | N-(4,6-DIMETHYL-PYRIMIDIN-2-YL)-N'-(2-METHOXY-6-TRIFLUOROMETHY L-PHENYLSULPHONYL)-UREA | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153463-A1 | Substituted aryl sulphonyl(thio)ureas | TST, DDT, CBR3 | GAA 3660/4885MAPT 4329/4885TP53 2774/4885 |
| US-20050004123-A1 | Substituted aryl sulphonyl(thio)ureas used as herbicides | DDT, CBR3, TST | GAA 3670/4885MAPT 4114/4885TP53 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.