SCHEMBL358921

SCHEMBL358921

NC(=O)[C@@H](N)Cc1c[nH]cn1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 1/20 0.35
CYP3A4 P08684 1/20 0.33
SLC7A5 Q01650 1/20 0.33
SCN9A Q15858 2/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43003 1.00 SCN10A (0.35) SCN10ACYP3A4SLC7A5SCN9ACYP1A2
SCHEMBL5101793 1.00 SCN10A (0.35) SCN10ACYP3A4SLC7A5SCN9ACYP1A2
Hydrochloric Acid SCHEMBL9767617 0.98 SCN10A (0.34) SCN10ACYP3A4SLC7A5SCN9ACYP1A2
Hydrochloric Acid SCHEMBL28902277 0.98 SCN10A (0.34) SCN10ACYP3A4SLC7A5SCN9ACYP1A2
Hydrochloric Acid SCHEMBL14831325 0.98 SCN10A (0.34) SCN10ACYP3A4SLC7A5SCN9ACYP1A2
Hydrochloric Acid SCHEMBL9767618 0.98 SCN10A (0.34) SCN10ACYP3A4SLC7A5SCN9ACYP1A2
Hydrochloric Acid SCHEMBL6280216 0.98 SCN10A (0.34) SCN10ACYP3A4SLC7A5SCN9ACYP1A2
Hydrochloric Acid SCHEMBL9767650 0.97 CYP1A2 (0.34) SCN10ACYP3A4SLC7A5SCN9ACYP1A2
Histidine SCHEMBL27646599 0.94 SLC7A5 (0.43) CYP3A4SLC7A5CYP1A2
Histidine SCHEMBL5221755 0.86 CYP1A2 (0.47) CYP3A4SLC7A5CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043394-A1 KIT FOR FORMING SUPRAMOLECULAR SELF-ASSEMBLY COMPLEX AND USE THEREOF 北京睿创康泰医药研究院有限公司 2025-03-06 WO claimed
WO-2025048497-A1 NOVEL HISTIDINE AMIDE CHOLESTEROL COMPOUND, AND RNA DELIVERY LIPID NANOPARTICLES COMPRISING SAME 충남대학교산학협력단 2025-03-06 WO claimed
EP-4415561-A2 ORGANIC COMPOUNDS Givaudan SA (CH) 2024-08-21 EP claimed
US-20240025949-A1 Beta-Arrestin Effectors and Compositions and Methods of Use Thereof TREVENA, INC. 2024-01-25 US claimed
WO-2023062110-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2023-04-20 WO claimed
US-20220315797-A1 COMBINED USE OF POLYOL ESTERS AND CATIONIC POLYELECTROLYTES IN AQUEOUS POLYURETHANE DISPERSIONS EVONIK OPERATIONS GMBH (DE) 2022-10-06 US claimed
US-20220259429-A1 COMBINED USE OF POLYOL ETHERS AND CATIONIC POLYELECTROLYTES IN AQUEOUS POLYURETHANE DISPERSIONS EVONIK OPERATIONS GMBH (DE) 2022-08-18 US claimed
EP-3999224-A1 COMBINED USE OF POLYOL ETHERS AND CATIONIC POLYELECTROLYTES IN AQUEOUS POLYURETHANE DISPERSIONS Evonik Operations GmbH (DE) 2022-05-25 EP claimed
EP-3999602-A1 COMBINED USE OF POLYOL ESTERS AND CATIONIC POLYELECTROLYTES IN AQUEOUS POLYURETHANE DISPERSIONS Evonik Operations GmbH (DE) 2022-05-25 EP claimed
WO-2021216529-A1 β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF TREVENA, INC. (US) 2021-10-28 WO claimed
EP-1833832-A1 NAPTHYRIDINE COMPOUNDS AS ROCK INHIBITORS GPC Biotech AG (DE) 2007-09-19 EP claimed
WO-2007060028-A1 NAPTHYRIDINE COMPOUNDS AS ROCK INHIBITORS GPC BIOTECH AG (DE) 2007-05-31 WO claimed
US-6949658-B2 Process for producing optically active α-amino acid and optically active α-amino acid amide MITSUBISHI RAYON CO., LTD. (JP) 2005-09-27 US claimed
EP-1417190-A1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR Amgen Inc. (US) 2004-05-12 EP claimed
WO-2003009850-A1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEN INC. (US) 2003-02-06 WO claimed
US-5486595-A Tumor necrosis factor inhibitors CENTECOR, INC. (US) 1996-01-23 US claimed
WO-1995026744-A1 TUMOR NECROSIS FACTOR INHIBITORS CENTOCOR, INC. (US) 1995-10-12 WO claimed
EP-0473700-A1 AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES NOVO NORDISK A/S (DK) 1992-03-11 EP claimed
WO-1990014429-A1 AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES NOVO NORDISK A/S (DK) 1990-11-29 WO claimed
EP-0371543-A2 Gastrin releasing peptide antagonists MERCK & CO. INC. (US) 1990-06-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025949-A1 Beta-Arrestin Effectors and Compositions and Methods of Use Thereof ARRB1, FGB, SARS1 SCN10A 2292/4885CYP3A4 4383/4885SLC7A5 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.